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Blood Loss, Surgical clinical trials

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NCT ID: NCT04143373 Completed - Surgical Blood Loss Clinical Trials

Effect of Warm Saline Irrigation on Bleeding in Mandibular Third Molar Surgery

Start date: October 1, 2017
Phase: N/A
Study type: Interventional

The objective of this research is to compare the effect of irrigation during impacted mandibular third molar surgery, with normal saline of 25 ± 2 ° C and 37 ± 1 ° C for control and experimental sides, respectively.

NCT ID: NCT04116385 Completed - Clinical trials for Blood Loss, Surgical

Evaluation of the Quantra System in a Surgical Oncological Population

Start date: August 15, 2019
Phase:
Study type: Observational

This study will monitor coagulation parameters during the perioperative course of cancer surgical procedures using the Quantra System with the QPlus Cartridge.

NCT ID: NCT04114253 Completed - Clinical trials for Blood Loss, Surgical

QStat in Liver Transplant

Start date: September 4, 2019
Phase:
Study type: Observational

This study will assess the clinical performance of the Quantra System with the QStat Cartridge in the liver transplant population.

NCT ID: NCT04095754 Completed - Clinical trials for Intra-operative Bleeding

Can Head Position Improve Surgical Field During Ear Surgery?

Start date: April 12, 2020
Phase: N/A
Study type: Interventional

Middle ear surgeries utilizes microscope in a narrow field. They are better performed under controlled hypotension, to minimize bleeding and improve surgical field visualization and hence improve results.Head-up or anti-trendelenburg position influences intraoperative bleeding by generating regional ischaemia in sites elevated above the level of the heart. Also by augmenting the effect of vasodilators through pooling of blood in dilated veins.

NCT ID: NCT04040023 Completed - Surgical Blood Loss Clinical Trials

Patient Blood Management in Cardiac Surgery

PBMc
Start date: September 10, 2019
Phase: N/A
Study type: Interventional

Preoperative anemia is associated with an important increase in transfusions of red blood cells (RBC) compared to a non-anemic patient in cardiac and non cardiac surgery. Furthermore transfusion is also an independent factor of morbi-mortality with notably an increase in the infectious risk, immunological, an increase of the risk of cardiac decompensation, respiratory decompensation Transfusion Related Acute Lung Injury (TRALI) or Transfusion Associated Cardiac Overload (TACO), and an increase in mortality of 16%. Management of perioperative transfusion is therefore a public health issue. Since 2010, the World Health Organization (WHO) has been promoting a systematic approach to implement blood management programs for the patient to optimize the use of resources and promote quality and safety of care. Improving the relevance of transfusion in cardiac surgery could be achieved by optimizing the management of patients around 2 axis: A:non-drug intervention : Review of Practices to Improve the Management of Perioperative RBC Transfusion B:drug intervention : Systematic correction of pre- and postoperative iron, vitamin deficiencies and anemia The aim of this program is to improve the relevance of transfusion in cardiac surgery and to limit the morbidity and mortality induced by transfusion. This program is part of a global project of pre, per and postoperative management of the patient undergoing cardiac surgery programmed under extracorporeal circulation (ECC). It requires a multidisciplinary approach between cardiologists, anesthesiologists and intensivists, perfusionists, cardiac surgeons and paramedical teams to optimize the management of the patient.

NCT ID: NCT04025736 Completed - Rotator Cuff Tears Clinical Trials

Arthroscopic Shoulder Surgery With Administration of Intravenous Tranexamic Acid

Start date: June 7, 2017
Phase: N/A
Study type: Interventional

Purpose: The study aimed to determine whether intravenous administration of tanexamic acid (TXA) before shoulder arthroscopic rotator cuff repair surgery can improve arthroscopy visual clarity. Methods: This is a prospective, double-blinded, randomized and placebo-controlled study. From May 2016 to April 2018, patients requiring arthroscopic rotator cuff repair were enrolled and randomly assigned to either the TXA group that received 1000mg tranexamic acid intravenously 10 minutes before surgery or the placebo group that received the same volume of plain saline. Patients with pre-existing liver/renal disease, coagulopathy, or concurrent use of anti-coagulation medications were excluded. The visual clarity was rated by a numeric rating scale from grade 1(poor) to grade 3(clear) every 15 minutes throughout the surgery. Secondary outcomes included estimated perioperative blood loss, operative time, degree of shoulder swelling, postoperative subjective pain score, inpatient duration and associated comorbidities were recorded. Both parametric and nonparametric methods were used for statistical analysis.

NCT ID: NCT03988465 Completed - Clinical trials for Blood Loss, Surgical

HemoSonics - UTMB Cardiac Surgery Study

Start date: June 19, 2019
Phase:
Study type: Observational

This study will evaluate the performance of the Quantra System comprised of the Quantra Hemostasis Analyzer with the Quantra QPlus Cartridge in patients undergoing cardiac surgery utilizing cardiopulmonary bypass, including the placement of a ventricular access device.

NCT ID: NCT03984851 Completed - Surgical Blood Loss Clinical Trials

Hemostasis Using Surgicel in Pediatric Tonsillectomy

Start date: January 1, 2016
Phase:
Study type: Observational

Tonsillectomy is one of the commonest procedures performed in otolaryngology and one of its major complications is post-tonsillectomy bleeding. The goal of this study was to assess the effectiveness of Surgicel without bipolar cautery in achieving primary hemostasis in tonsillectomy. The patient that were enrolled in this retrospective study were patients who underwent tonsillectomy and achieved hemostasis either by Surgicel (group A) or bipolar cautery (group B). Our results showed that there was no statistical significant difference between the two techniques in terms of post-operative bleeding events.

NCT ID: NCT03967171 Completed - Postoperative Pain Clinical Trials

The Comparison of the Effect of Different Oxytocin Administrations on the Blood Loss During Cesarean Delivery

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

This study compares the effect of starting intravenous oxytocin infusion early before uterine incision versus late after umbilical cord clamping on the blood loss during elective cesarean section

NCT ID: NCT03952546 Completed - Surgical Blood Loss Clinical Trials

To Evaluate the Safety and Efficacy of the Saline-coupled Bipolar Sealer in Primary Unilateral Total Knee Arthroplasty

Start date: May 7, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate whether the saline-coupled bipolar sealer compared to the unipolar electrocautery provides superior hemostasis in patients undergoing primary unilateral total knee arthroplasty. This will be a prospective, randomized, single-blinded, non-inferiority study in patients scheduled for a primary unilateral total knee arthroplasty (TKA) with Dr. Eugene Krauss or Dr. Ayal Segal. The restriction of this study to two surgeons will limit variations in the outcomes being measured due to differences in surgical technique.