The Glycemic and Insulinemic Responses Elicited by Meals Containing Whole Grain Rye Bread or White Wheat Bread

Blood Glucose Concentration Clinical Trial

Official title:

The Effects of Margarine and Ham or Vegetable Soup on the on the Glycemic and Insulinemic Responses Elicited by Whole Grain Rye Bread or White Wheat Bread

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT02400411
• Other study ID #: HY_RAV_Breadmeal
• Status: Active, not recruiting
• Phase: N/A
• First received: March 17, 2015
• Last updated: September 3, 2015
• Start date: March 2015

Study information

• Verified date: September 2015
• Source: Helsinki University
• Contact: n/a
• Is FDA regulated: No
• Health authority: Finland: Ethics Committee
• Study type: Interventional

Clinical Trial Summary

This is a postprandial study with healthy volunteers. The glycemic and insulinemic responses elicited by meals containing either whole grain rye bread or white wheat bread as such or combined with margarine and ham and vegetable soup are compared. Blood glucose concentrations are monitored from finger prick blood samples collected before the meal and at 15, 30, 45, 60, 90 and 120 min. Venous samples for insulin concentrations are taken at time-points 0, 30 and 60 min.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 15
• Est. primary completion date: October 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• female

• BMI 18-27 kg/m2

Exclusion Criteria:

• pregnant or breastfeeding

• diabetes, gastrointestinal disease

• regular use of medication

• strict vegetarian or vegan diet

• food allergy

• recent blood donation

Study Design

Allocation: Randomized, Endpoint Classification: Bio-availability Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Outcomes Assessor)

Related Conditions & MeSH terms

• Blood Glucose Concentration

Intervention

Other:
• Wheat bread

• margarine

• ham

• soup

• rye bread

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Helsinki University	Fazer Group

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Blood glucose concentration		120 min	No
Secondary	Serum insulin concentration		60 min	No