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Blood Flow Restriction clinical trials

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NCT ID: NCT06171841 Active, not recruiting - Resistance Training Clinical Trials

Effects of Low-Intensity Blood Flow Restriction Training in Normoxia and Hypoxia Conditions

Start date: November 20, 2023
Phase: N/A
Study type: Interventional

One approach to significantly reducing resistance training intensity while maintaining effectiveness in muscle mass and strength development involves conducting training sessions under hypoxic conditions. This is likely due to heightened physiological responses. While sports science research indicates a substantial impact of hypoxic conditions on immediate increases in metabolic stress and augmented hormonal responses, recent findings suggest that the role of their influence on skeletal muscle adaptations post-resistance training under hypoxic conditions remains unknown. Additionally, there is a lack of reports on whether the type of hypoxia applied via blood flow restriction or chamber differentiates the increase in secretion of these catecholamines in both immediate and long-term aspects.

NCT ID: NCT05606744 Not yet recruiting - Clinical trials for Blood Flow Restriction

Effects of Blood Flow Restriction During Eccentric Resistance Exercise

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the muscle strength and muscle soreness effects experienced following short term (acute) eccentric exercise with and without blood flow restriction (BFR) performed at low - moderate training intensities.

NCT ID: NCT05177952 Completed - Multiple Sclerosis Clinical Trials

Low-Load Blood Flow Restriction on Patients With Multiple Sclerosis

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

This research is being done to compare the current standard of care for strength training for patients with Multiple Sclerosis to lightweight resistance training with blood flow restriction.

NCT ID: NCT04996680 Completed - Clinical trials for Blood Flow Restriction

Vascular Occlusion for Optimizing Functional Improvement in Patients With Knee Osteoarthritis

VOFIKO
Start date: July 14, 2021
Phase: N/A
Study type: Interventional

Recent research in strength training physiology revealed that implementation of occlusion garments around the proximal aspect of the lower limbs in combination with low load strength training causes a reduced blood flow and thus providing a high metabolic stimulus, causing a training effect similar to high load training. This study will investigate the added effect of BFR focussing on functional outcome, pain-management and lower limb strength in patients with knee osteoarthritis. Therefore, 234 patiens will be divided into three equal groups (n=78), (control group, sham group and BFR-group) which will be subjected to a 12-week during standard strength training program, 2 times a week for 60 minutes. The first group, which will be submitted to low load resistance training commonly used in contemporary physiotherapy for OA, will serve as a control group whereas both the BFRT and Sham groups will objectify the additional value of implementing vascular occlusion in respective low load resistance training protocol.

NCT ID: NCT04977804 Withdrawn - Clinical trials for Blood Flow Restriction

Eccentric Resistance Training With Blood Flow Restriction on Muscle Function

Start date: March 30, 2024
Phase: N/A
Study type: Interventional

The study will determine the effects of adding blood flow restriction to eccentric training to assess whether this increases the improvements of muscle strength and size.

NCT ID: NCT04384120 Recruiting - Clinical trials for Blood Flow Restriction

BFR Therapy in Patients With Rotator Cuff Tears

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the effect of utilizing blood flow restriction (BFR) therapy in patients treated both non operatively and operatively for rotator cuff tears (RCT). BFR has been proposed to work by restricting arterial inflow leading to an oxygen depleted environment and the ability to induce muscle adaption at lower maximum repetition via reactive hyperemia. Muscle atrophy occurs following rotator cuff tear. Thus, physical therapy is used to regain strength with the ultimate goal of returning to activity. The goal of this investigation is to determine if using BFR during therapy for non-operatively managed and operatively managed rotator cuff tears would lead to increased and expedited strength gains. Additionally the investigators would like to determine if BFR is beneficial in preventing muscle atrophy and fatty infiltration often seen in the setting of rotator cuff tear, as it is known that cuff tears can subject the muscles to degenerative changes and these patients are at risk for poorer clinical outcomes. The investigators will also look at patient reported outcomes metrics and pain scores to determine if BFR has a significant impact on the patient experience surrounding rotator cuff tear after both nonoperative treatment with therapy and operative treatment with surgical repair and peri-operative rehabilitation. The investigators hypothesize that the BFR group will have significantly greater strength gains at all time points. Previous studies have shown that BFR has potential in increasing muscle torque generation and cross sectional area in the first six months following anterior cruciate ligament (ACL) reconstruction. While there have not been as many studies investigating the use of BFR following upper extremity surgery, previous research has demonstrate that BFR can be useful both proximal and distal to the targeted muscle groups in the upper extremity. In addition to the paucity of research on post-operative BFR following rotator cuff repair (RCR), there is no evidence on pre-operative use as well. The investigators believe that the use of BFR in the perioperative period surrounding rotator cuff tear and repair has the potential to significantly decrease muscle atrophy and lead to faster, more substantial strength gains and less muscle atrophy and fatty infiltration.

NCT ID: NCT04285879 Completed - ACL Injury Clinical Trials

Blood Flow Restriction Training (BFR) in an Adolescent Population

Start date: December 15, 2020
Phase: N/A
Study type: Interventional

While there are a number studies that have reported on the use of BFR in the adult population, there is limited information about the use of BFR in the adolescent population. This study aims to evaluate the use of BFR training in conjunction with traditional ACL (anterior cruciate ligament) reconstruction rehabilitation in adolescents. The purpose of this study is to evaluate the addition of BFR-based exercise to traditional methods of physical therapy. Does the use of BFR-based exercise improve strength, hypertrophy, functional and patient reported outcomes after ACL Reconstruction in the adolescent population?

NCT ID: NCT04270695 Completed - Clinical trials for Blood Flow Restriction

Blood Flow Restriction Training Combined With Abdominal draw-in Maneuver on Transverse Abdominis Strengthening

Start date: March 3, 2020
Phase: N/A
Study type: Interventional

This study expects to provide a new alternative way to improve the muscle activation, strength and activation of transverse abdominis in abdominal draw-in maneuver combined with blood flow restriction.

NCT ID: NCT04079010 Completed - Clinical trials for Blood Flow Restriction

The Effect of Blood Flow Restriction With and Without Arginine on Physical Performance and Growth Hormone

Start date: September 4, 2019
Phase: N/A
Study type: Interventional

The current study will investigate the effects of Blood Flow Restriction (BFR) training and L-arginine supplementation on recreationally trained female participants. In particular, it will compare performance outcomes and blood markers among two intervention groups (BFR and BFR+Arg) and a control group (CON).