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Blindness clinical trials

View clinical trials related to Blindness.

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NCT ID: NCT06318000 Completed - Visual Impairment Clinical Trials

Physical Activity and Sports for People With Visual Impairments

Start date: March 1, 2020
Phase:
Study type: Observational

Purpose of this study was to assess the relationship between the visual impairment degree and the level of children's fundamental motor skills, balance and bilateral coordination.

NCT ID: NCT05643222 Completed - Clinical trials for Color Vision Defects

Performance of Red Tinted Contact Lenses on Colour Defects

CL
Start date: October 20, 2020
Phase: N/A
Study type: Interventional

This study aimed to relate and compare the performance of 4 types of red-tinted contact lenses (CL) with the Total Error Score (TES) from the Farnsworth-Munsell 100 Hue test on colour deficient subjects. Only 6 subject with colour vision defect was tested in this study.

NCT ID: NCT05608811 Completed - Blindness Clinical Trials

The Effect of Social Skills Training in Visually Impaired Adolescents

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

The aim of our study is to examine the effects of eight sessions of online social skills training given to visually impaired adolescents on social skills, self-efficacy, social phobia and social integration. Forty visually impaired adolescents between the ages of 13 and 19 participated in the study. Participants were divided into control and training groups. 20 adolescents were included in the education program. All participants included in the study were evaluated using the Sociodemographic Information Form, Social Skills Assessment Scale for Children, General Self-Efficacy Scale, Child and Adolescent Social Phobia Scale, and Social Integration Questionnaire.

NCT ID: NCT05463016 Completed - Clinical trials for Color Vision Defects

Impact of Color Correcting Lenses on Color Vision Deficiency

Start date: July 28, 2022
Phase: N/A
Study type: Interventional

To demonstrate improved color vision in subjects with color vision deficiencies while wearing color-correcting lenses and after color-correcting lense use.

NCT ID: NCT05144906 Completed - Blindness Clinical Trials

Implicit Attitudes Toward Body Shape Among Blind Women

Start date: December 1, 2021
Phase:
Study type: Observational

High levels of body image concerns and disordered eating in western women have been associated with the promotion of an unrealistically thin body ideal. The pressure to conform with the thin-ideal forms both explicit and implicit attitudes favoring thinness. Visual-based media depicting thin-idealized bodies plays a major role in forming such attitudes. However, attitudes favoring thinness can also be transmitted through non-visual communication such as peer pressure and significant others. The current study will examine if implicit attitudes favoring thinness and disliking overweight bodies can be formed without ever being exposed to visual-based media or being visually exposed to body shapes. To achieve this goal, the study will assess implicit attitudes towards thin and overweight bodies in congenitally blind women and those who were blinded early in life. The assessment will be carried out using a novel auditory weight-bias implicit association test.

NCT ID: NCT04985097 Completed - Clinical trials for Visual Acuity Reduced Transiently

Home-based Visual Training in Patients Implanted With Trifocal Diffractive Intraocular Lenses

OPTicTRAIN
Start date: September 1, 2018
Phase: N/A
Study type: Interventional

This multicentre randomised controlled trial aimed to reduce the visual discomfort that patients implanted with trifocal diffractive intraocular lenses may experience after surgery. To this end, a visual training software (Optictrain) was developed in which Gabor patches were presented to the patient on a hand-held electronic device. Patients who met all inclusion criteria and consented to participate underwent half an hour of visual training per day for a period of 20 consecutive days remotely on a colourimetrically characterised Samsung Galaxy Tab A device on which the Optictrain software (n=30) or a placebo software (n=30), respectively, was pre-installed. Corrected and uncorrected near, intermediate and distance visual acuity (VA) and mesopic near and distance contrast sensitivity (CS) were measured monocularly and binocularly at two visits: during the first postoperative week (V0) and after 20 days of visual training with the assigned software (V1). The statistical analysis of the results obtained in the study has not yet been carried out.

NCT ID: NCT04936100 Completed - Blindness Clinical Trials

Assessment of the Validity, Reliability, and Feasibility of Two Smartphone Applications for Testing the Visual Acuity

Start date: June 23, 2021
Phase: N/A
Study type: Interventional

Visual acuity (VA) is the most common measure of visual function globally. In clinical settings and during screening events, VA is an important measure to quantify changes in vision over time. Additionally, in the context of epidemiological studies and population-based surveys, VA is a critical measure to determine the presence and degree of vision impairment and to report on the indicators of effective eye care service coverage (i.e. refractive error and cataract surgery), that are currently considered by World Health Organization (WHO) for monitoring progress towards the Universal Health Coverage. There are numerous applications for assessing VA; however, the number of validated applications is limited. In this study, the investigators aim to evaluate the external validity, intra- and inter-observer reliability, and feasibility of two applications ("Easy Vision" and "Peek Acuity") for testing the visual acuity.

NCT ID: NCT04560790 Completed - Cornea Clinical Trials

Safety and Efficacy of CRISPR/Cas9 mRNA Instantaneous Gene Editing Therapy to Treat Refractory Viral Keratitis

Start date: November 4, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability and efficacy of a single escalating doses of BD111 CRISPR/Cas9 mRNA Instantaneous Gene Editing Therapy administered via corneal injection in participants with refractory herpetic viral keratitis.

NCT ID: NCT04525261 Completed - Clinical trials for Leber Congenital Amaurosis 2

Natural History of Patients With Inherited Retinal Diseases Due to Mutations in RPE65 Gene

RPE65-NHS
Start date: May 1, 2020
Phase:
Study type: Observational

Rationale: In preparation for treatment with gene therapy, this study is being conducted in order to investigate the natural history of Inherited Retinal Dystrophies (IRDs) due to mutations in RPE65 gene. Such a study will help identify suitable patients for therapeutic intervention. Methodology: This is a multicenter retrospective, descriptive chart review study designed to assess retinal structure and function in subjects with IRDs due to mutation in RPE65 gene by visual acuity, visual field measurements, Optical Coherence Tomography (OCT), and a number of other vision-related assessments.

NCT ID: NCT04143334 Completed - Cataract Clinical Trials

Prevalence of Blindness, Visual Impairment in Chao Nan Area, China

Start date: April 1, 2012
Phase:
Study type: Observational

This study will provide a profile of blindness/visual impairment, avoidable blindness and cataract surgery service in Chaonan, mainland China. We also evaluate the diagnostic accuracy of Rapid Assessment of Avoidable Blindness (RAAB) comparison with conventional survey.