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Blast Injuries clinical trials

View clinical trials related to Blast Injuries.

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NCT ID: NCT05183087 Completed - Clinical trials for Traumatic Brain Injury

Long-Term Effects of Repetitive, Low-Level Blast Exposure on Special Operations Forces Service Members

ReBlast
Start date: July 1, 2021
Phase:
Study type: Observational

This is a pilot study to identify biomarkers that individually, and in combination, demonstrate the greatest sensitivity to repetitive, low-level blast exposure (RLLBE) neurotrauma in Special Operations Forces (SOF) personnel. The proposed cross-sectional, multimodal study will elucidate the potential effects of long-term RLLBE by comparing biomarkers across subjects.

NCT ID: NCT03358758 Completed - Wounds and Injuries Clinical Trials

Retrospective Morbidity and Mortality Study of Conflict-Related Injuries: Erbil, Iraq

Start date: October 16, 2016
Phase: N/A
Study type: Observational

A retrospective morbidity and mortality study, using routinely collected data, investigating the epidemiology of patients with conflict-related injuries presenting to a dedicated trauma hospital in Erbil, Iraq, during the campaign to liberate Mosul from ISIS.

NCT ID: NCT01990547 Completed - Clinical trials for Post-Traumatic Stress Disorder

Virtual Reality Therapy and Imaging in Combat Veterans With Blast Injury and Posttraumatic Stress Disorder

ViRTICo-BP
Start date: n/a
Phase: N/A
Study type: Observational

The main purpose of this study is to determine whether functional magnetic resonance imaging (fMRI), can distinguish between service members with and without traumatic brain injury (TBI), as well as those with posttraumatic stress disorder (PTSD) who receive either virtual reality exposure therapy (VRET) or PTSD treatment other than exposure therapy. The investigators and other investigators have previously identified changes in function in multiple regions of the brain in combat veterans with PTSD, and the investigators have also seen that structural changes in the white matter associated with combat TBI are also linked with changes in function, and in turn with PTSD symptoms. However, the investigators need to confirm these findings in larger numbers, and also need to discern whether fMRI can distinguish if there is something significantly different about those who have PTSD after TBI vs. those in whom it does not follow a TBI. Finally, the investigators have previously demonstrated that exposure therapy ameliorates the functional changes in the brain induced by PTSD, but the investigators do not know if similar changes occur with other forms of therapy, so the investigators seek to compare the two directly. It is our expectation that the findings will better inform the choice of therapy for service members with combat-related PTSD, with or without TBI.

NCT ID: NCT01596569 Completed - Clinical trials for Traumatic Brain Injury

Combined Transcranial Magnetic Stimulation and Cognitive Treatment in Blast Traumatic Brain Injury

COST-TBI
Start date: May 2012
Phase: N/A
Study type: Interventional

This study investigates the efficacy of a novel neurorehabilitation program combining noninvasive brain stimulation (transcranial magnetic stimulation or TMS) and cognitive therapy, on cognitive function and quality of life in individuals with blast-induced traumatic brain injury (bTBI).

NCT ID: NCT01567020 Completed - Brain Injuries Clinical Trials

Central Auditory Processing Deficits Associated With Blast Exposure

Start date: May 2012
Phase:
Study type: Observational [Patient Registry]

The current conflicts in Afghanistan and Iraq have resulted in unprecedented rates of exposure to high-intensity blasts and resulting brain injury. This research team has established that recently blast-exposed Soldiers show differences from controls on tests of central auditory function. This project will 1) develop a more accurate estimate of the prevalence of central auditory dysfunction among Veterans exposed to blasts over the past ten years, 2) identify the functional outcomes associated with abnormal performance on tests of central processing, and 3) improve understanding of the ways in which blast-exposure resembles and differs from both the normal aging process and non-blast-related TBI in terms of performance on tests of central auditory processing.

NCT ID: NCT01193686 Completed - Polytrauma Clinical Trials

Peer Visitation for OEF/OIF Veterans

Start date: November 2010
Phase: N/A
Study type: Interventional

The goal of this study was to train OIF/OIF Veterans with multiple injuries to be Peer Visitors, i.e., Volunteers who visit more recently OIF/OEF Veterans and provide support. We evaluated the effectiveness of the training, and any benefits that Volunteer Peer Visitors and the Recipients of Peer Visitors experienced as a result of participating in Peer Visitation.

NCT ID: NCT00872690 Completed - Brain Injuries Clinical Trials

Factors Affecting Return to Work Among OEF/OIF Veterans With Polytrauma

Start date: October 2010
Phase: N/A
Study type: Observational

The goal of this study is to examine things that make it easy or hard for OEF/OIF veterans with polytrauma to live independently or do things "on their own" at home and in the community.

NCT ID: NCT00857207 Completed - Brain Concussion Clinical Trials

Metacognitive Training to Enhance Strategy Use in Blast-Related TBI

Start date: October 1, 2013
Phase: N/A
Study type: Interventional

Enhanced Goal Management Training (GMT) is a 10-week group or individual therapy that teaches strategies to improve an individual's ability to complete everyday tasks. This research study will test the effect of GMT on 36 OEF/OIF Veterans compared to a control group of 16 OEF/OIF Veterans receiving a Brain Health Workshop. The results will provide information to conduct future research with a larger group of patients or to identify which patients demonstrate more benefit from the training.

NCT ID: NCT00414219 Completed - Clinical trials for Corneal Foreign Body Following Blast Injury

Visual Prognosis in Non-Penetrating Corneal Blast Injuries

Start date: November 2004
Phase: N/A
Study type: Observational

The purpose of this study is to assess visual quality of patients with non-penetrating, non-metallic, stable corneal foreign bodies. Visual quality will be assessed by examining visual acuity, wavefront analysis and contrast sensitivity. Drawings, photographs, and confocal microscopy will be used to document clinical examination of the cornea at baseline and on follow-up examinations.