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Bladder Urothelial Carcinoma clinical trials

View clinical trials related to Bladder Urothelial Carcinoma.

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NCT ID: NCT06416319 Recruiting - Bladder Cancer Clinical Trials

Preoperative Physical Activity Improvement With the Use of Activity Trackers Before Radical Cystectomy (PreAct)

PreAct
Start date: March 14, 2023
Phase: N/A
Study type: Interventional

A bicentric, open-label randomised controlled trial (RCT) is planned to investigate whether the use of fitness wristbands in a defined preoperative period prior to radical cystectomy leads to a preoperative increase in participants' physical activity (number of steps per day) up to the day of radical cystectomy.

NCT ID: NCT06170177 Recruiting - Bladder Cancer Clinical Trials

Study on the Quality of Life and Pathological State in Patients Who Underwent Radical Cystectomy

Start date: February 4, 2013
Phase:
Study type: Observational

Observational study on the quality of life and pathological state of patients underwent radical cystectomy.

NCT ID: NCT06167356 Recruiting - Bladder Cancer Clinical Trials

Study on the Occurrence of Possible Relapses and on the Quality of Life in Patients Who Underwent TURBK.

Start date: November 27, 2013
Phase:
Study type: Observational

A database has been created and will be used in which data will be collected in electronic format relating to adult patients who underwent one of the following endoscopic resection surgeries: TURBK, MAPPING, TURBK SECOND LOOK, BLADDER BIOPSIES.

NCT ID: NCT05833997 Recruiting - Bladder Cancer Clinical Trials

Safety Analysis and Oncological Outcomes in HoLERT vs TURBT

Start date: December 10, 2020
Phase: N/A
Study type: Interventional

Bladder urothelial cancer is the second most common urologic tumor and represents a worldwide public health problem. Most cases are diagnosed as non-muscle invasive tumors, and can be treated with transurethral resection of bladder tumor (TURBT). However, the electrical energy-based TURBT fragments the tumor, burning it to its own muscular layer leading to artifacts that may spoil the histopathological analysis, resulting in understaging after the first TURBT ranging from 30-64%, depending on the presence of detrusor muscle. Modern laser technologies have been emerging as an alternative to classical TURB using en bloc tumor resection technique (ERBT). Therefore, the laser is applied on tumor's pedicle to resect the whole and intact tumor without fragmentation or fulguration as occurs in TURBT. The purpose of using laser if to improve the resection quality, decrease intra and perioperative complications, avoid re-TURBT and reduce recurrence rates at the resection site and in distant sites. Thus, the purpose of this study is to evaluate Laser Holmium use for large tumors resection (>3cm), reducing complications, costs, and the need for new approaches, and improving the muscle layers samples.

NCT ID: NCT05788484 Recruiting - Colorectal Cancer Clinical Trials

A Study of CDX-585 in Patients With Advanced Malignancies

Start date: May 11, 2023
Phase: Phase 1
Study type: Interventional

This is an open-label, non-randomized, multicenter, dose-escalation and expansion study in patients with selected solid tumors.

NCT ID: NCT05669430 Recruiting - Clinical trials for Non-small Cell Lung Cancer

A Study of GV20-0251 in Patients With Solid Tumor Malignancies

Start date: March 23, 2023
Phase: Phase 1
Study type: Interventional

This is a Phase 1 study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to approved therapies or other standard of care.

NCT ID: NCT05296564 Recruiting - Clinical trials for Non Small Cell Lung Cancer

Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers

Start date: April 1, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

A Phase I/II Dose Escalation, Safety and Efficacy Study of HBI 0201-ESO TCRT (anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes) Given by Infusion to Patients with NY-ESO-1 -Expressing Metastatic Cancers

NCT ID: NCT05220124 Recruiting - Clinical trials for Bladder Urothelial Carcinoma

A Study of Probiotics Administration in the Immunotherapy of Urothelial Bladder Carcinoma

Start date: January 5, 2022
Phase: Phase 4
Study type: Interventional

A study of the efficacy and safety of probiotics in immunotherapy of urothelial carcinoma.

NCT ID: NCT05027412 Recruiting - Bladder Cancer Clinical Trials

En Bloc TURBT With Collins Loop vs Conventional TURBT

TURBT
Start date: April 1, 2021
Phase: N/A
Study type: Interventional

This is a prospective, randomized, randomized and single-blind study in patients diagnosed with primary bladder CV. Patients diagnosed by cystoscopy of a bladder tumor and with indication for endoscopic surgical treatment, who meet the inclusion criteria, and who sign the Informed Consent (IC), will be randomized.

NCT ID: NCT04985604 Recruiting - Colorectal Cancer Clinical Trials

Tovorafenib (DAY101) Monotherapy or in Combination With Other Therapies for Patients With Melanoma and Other Solid Tumors

Start date: July 15, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

This is a Phase 1b/2, multi-center, open label umbrella study of patients ≥12 years of age with recurrent, progressive, or refractory melanoma or other solid tumors with alterations in the key proteins of the RAS/RAF/MEK/ERK pathway, referred to as the MAPK pathway.