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Bladder Cancer clinical trials

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NCT ID: NCT06243510 Enrolling by invitation - Bladder Cancer Clinical Trials

Comparison of Apixaban Versus Enoxaparin

CARE
Start date: November 24, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized trial is to compare bladder cancer patient experiences taking prophylactic anticoagulation at home after surgery to remove their bladder. The main questions it aims to answer are: - Are patients equally adherent to apixaban as they are enoxaparin? Why or why not? - Do patients prefer apixaban or enoxaparin? - What is the typical patient cost to take apixaban vs enoxaparin after surgery? Participants will be randomized to receive a prescription for either enoxaparin or apixaban which they will then fill themselves and self-administer at home until post-operative day 30. They will receive phone calls from study coordinators at days 30 and 90 to complete questionaries over the phone to assess trial outcomes.

NCT ID: NCT05739071 Enrolling by invitation - Bladder Cancer Clinical Trials

JING SI HERBAL TEA and Urinary Tract Symptoms in Bladder Cancer

Start date: March 2023
Phase: N/A
Study type: Interventional

To identify the effects of JING SI HERBAL TEA in the treatment of lower urinary tract symptoms after intravesical therapy in patients with bladder cancer.

NCT ID: NCT05195515 Enrolling by invitation - Bladder Cancer Clinical Trials

The Impact of Late Effects After Treatment for Bladder Cancer on Quality of Life

CONQUER
Start date: January 1, 2022
Phase:
Study type: Observational [Patient Registry]

Bladder Cancer prognosis, treatment, and subsequent morbidity and mortality vary between the different stages, thus resulting in a different impact on patients' lives. There are some well known late effects of the treatments for bladder cancer, but the knowledge of their impact on patients Quality of Life is sparse. This study aims to determine the prevalence of late effects impact on Quality of Life and potential risk factors for impairment.

NCT ID: NCT04939194 Enrolling by invitation - Bladder Cancer Clinical Trials

Fast Track Protocol After Radical Cystectomy and Urinary Diversion: A Randomised Controlled Trial.

Start date: January 15, 2021
Phase: Phase 3
Study type: Interventional

We will design a randomized controlled single center study in which we will compare 2 groups of patients, 1 with standard perioperative protocols and another one in which we will apply fast track protocols in patients after radical cystectomy and urinary diversion .

NCT ID: NCT02609269 Enrolling by invitation - Prostate Cancer Clinical Trials

Decipher Genomics Resource for Intelligent Discovery

GRID®
Start date: October 2015
Phase:
Study type: Observational [Patient Registry]

To prospectively evaluate the utility of genomic expression data as a tool to better characterize the tumors of individual patients, and to understand how genomic information from individual patients undergoing routine clinical testing can be used in population-level analysis to improve treatment and outcomes.

NCT ID: NCT02074241 Enrolling by invitation - Bladder Cancer Clinical Trials

Molecular Markers of Chemosensitivity for Bladder Cancer

Start date: March 2014
Phase: N/A
Study type: Observational

The purpose of this study is to try to figure out some bio-markers of chemosensitivity for adjuvant chemotherapy for bladder cancer.

NCT ID: NCT02074189 Enrolling by invitation - Bladder Cancer Clinical Trials

Adjuvant Chemotherapy Following Radical Cystectomy to Treat Locally Advanced Bladder Cancer

Start date: March 2014
Phase: Phase 3
Study type: Interventional

Effect of adjuvant chemotherapy to control tumor progression in patients after cystectomy for locally advanced bladder cancer.

NCT ID: NCT00867620 Enrolling by invitation - Bladder Cancer Clinical Trials

Development of a Non-Invasive DNA Methylation-Based Assay System for the Risk Assessment of Urothelial Carcinoma

Start date: August 2008
Phase: N/A
Study type: Observational

Bladder cancer ranks the ninth in worldwide cancer incidence. Approximate 90% of bladder cancer is the malignancy of urothelium tissues, the urothelial cancer (UC). The mortality of bladder cancer is mainly due to recurrence and metastasis. Unfortunately, the currently available cytology or cystoscopy examination is of limited value because of low sensitivity of early disease. New biomarkers as well as detection technology are thus required to improve early diagnosis. By the aid of quantitative methylation-specific PCR (QMSP), which allows detecting tumor-derived DNA from tissues and body fluids, DNA methylation-based assay is thus developing for early detection and prognosis. The goal of this proposed project is to develop a panel of DNA-methylation based biomarkers for UC diagnosis, prognosis, and prediction of responses to therapy (especially the recurrence, invasion, survival, and responses to therapeutic agents). Although numerous studies have investigated the aberrant promoter hypermethylation in bladder cancers or UC, inconsistent results are observed. DNA hypermethylation determination may rely on not only the conditions of QMSP, but also the biopsy specimens of different race, environmental expose factors, and regional variation. We thus need to profile the DNA methylation pattern of UC patients in Taiwan to establish a panel of potential prediction biomarkers for local patients.