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Bladder Cancer clinical trials

View clinical trials related to Bladder Cancer.

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NCT ID: NCT06334406 Not yet recruiting - Bladder Cancer Clinical Trials

Antitumor T Cell Responses in Patients With Bladder Cancer

immunoBLAD
Start date: April 2, 2024
Phase:
Study type: Observational

The main objective of this study is to evaluate the induction of Th1 anti-TERT responses by treatments in patients with bladder tumor.

NCT ID: NCT06331299 Not yet recruiting - Bladder Cancer Clinical Trials

A Phase 3 Study of UGN-103 for Treatment of Patients With Low-grade Intermediate-risk Non-muscle Invasive Bladder Cancer

UTOPIA
Start date: July 2024
Phase: Phase 3
Study type: Interventional

This Phase 3, single-arm, multicenter study will evaluate the efficacy and safety of UGN-103, a novel formulation of UGN-102, instilled in the urinary bladder of patients with low-grade non-muscle invasive bladder cancer (LG-NMIBC).

NCT ID: NCT06324058 Not yet recruiting - Bladder Cancer Clinical Trials

Cryoablation Versus BCG Instillation Therapy for High-risk NMIBC

Start date: March 18, 2024
Phase: N/A
Study type: Interventional

This trial plans to enroll 190 eligible patients and randomize them into two groups with a 1:1 ratio, with 95 patients in each group. The experimental group will receive immediate cryoablation therapy at the resection site after TUR, while the control group will only undergo TUR and receive conventional BCG instillation therapy postoperatively. Both groups of subjects will undergo Re-TURBT or cystoscopy 10-12 weeks after surgery to compare the tumor-free residual rates and adverse events between the two groups.

NCT ID: NCT06310369 Not yet recruiting - Bladder Cancer Clinical Trials

Radiotherapy for BCG-unresponsive Non-muscle-invasive Carcinoma in Situ (CIS) Bladder Cancer

Start date: March 1, 2025
Phase: Phase 2
Study type: Interventional

We aim to investigate a possible role for radiotherapy in good prognosis bladder cancer patients has been identified as a possible alternative to cystectomy, especially for patients non-eligible for surgery but has yet to be fully explored.

NCT ID: NCT06305767 Recruiting - Bladder Cancer Clinical Trials

A Study of Pembrolizumab (MK-3475) Plus V940 in Participants With Bladder Cancer Post-Radical Resection (V940-005)

Start date: March 28, 2024
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety and efficacy of V940 in combination with pembrolizumab (MK-3475) compared to pembrolizumab alone as an adjuvant treatment for participants with pathologic high-risk muscle-invasive urothelial carcinoma (MIUC) after radical resection. The primary study hypothesis is that V940 in combination with pembrolizumab results in a superior disease-free survival (DFS) as assessed by the investigator compared to pembrolizumab alone in participants with high-risk MIUC after radical resection.

NCT ID: NCT06301308 Withdrawn - Bladder Cancer Clinical Trials

A Novel Application of 2% Lidocaine Injection for Male Rigid cycstoscopy-a Patient-blinded Randomised Trial

Start date: October 1, 2023
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to learn about a novel application of lidocaine injection in male patients who needs rigid cycstoscopy test. The main question it aims to answer is:Does New Application of Lidocaine Liquid Provide Pain Relief for Patients During Cystoscopy? Before the cycstoscopy,Participants will be randomly divided into three different anesthesia mode groups,namely are Group A (intraurethral lidocaine gel alone), Group B (intraurethral lidocaine gel + lidocaine 2% injection), and Group C (intraurethral lidocaine gel + liquid paraffinl).Patients only need to prepare and cooperate according to routine surgical operations,which is group B or group C.

NCT ID: NCT06294054 Active, not recruiting - Bladder Cancer Clinical Trials

Bladder Cancer and Neoadjuvant Chemotherapy Efficiency Before Cystectomy

SELECT
Start date: April 1, 2023
Phase:
Study type: Observational

This study will allow the investigators to better assess the efficiency of neoadjuvant chemotherapy before cystectomy by training a predictive model on different patient cohorts with bladder cancer.

NCT ID: NCT06281080 Not yet recruiting - Bladder Cancer Clinical Trials

First-in-Human Trial of a Novel Endoluminal Robotic System for En-Bloc Resection of Bladder Tumours

Start date: July 1, 2024
Phase: N/A
Study type: Interventional

This is a prospective, single-arm study to evaluate the feasibility and safety of performing transurethral en-bloc resection of bladder tumours using the Zenith robotic system.

NCT ID: NCT06269536 Recruiting - Bladder Cancer Clinical Trials

Stress-reducing Intervention in Urothelial Carcinoma

Start date: February 15, 2024
Phase: N/A
Study type: Interventional

The aim of this interventional study is to test the heart-rate variability biofeedback intervention (HRV BI) in patients with muscle-infiltrating bladder carcinoma (MIBC) treated with chemotherapy based on cisplatin in neoadjuvant setting followed by local therapy (standard of care, SOC) compared to SOC alone.

NCT ID: NCT06255964 Not yet recruiting - Bladder Cancer Clinical Trials

A Study of IAP0971 in Combination With Bacillus Calmette Guerin in High Risk Non-muscular Invasive Bladder Cancer

Start date: February 15, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The efficacy and safety of IAP0971 single drug or combined with BCG intravesical instillation in the treatment of high-risk non muscle invasive bladder cancer with BCG treatment failure.