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Birth Weight clinical trials

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NCT ID: NCT03757780 Recruiting - Clinical trials for Low; Birthweight, Extremely (999 Grams or Less)

Low Birth Weight Fetuses With Caffeine Use

Start date: November 30, 2018
Phase:
Study type: Observational

Globally, it has been estimated that 15.5% of all infantsare born low birth weight, defined as birthweight less than 2,500 g .

NCT ID: NCT03545204 Recruiting - Clinical trials for Low-Birth-Weight Infant

Implementation Research of Kangaroo Mother Care in Rural Pakistan.

KMC
Start date: February 1, 2019
Phase: N/A
Study type: Interventional

Pakistan has a high neonatal mortality rate (55/1000 live birth)(1) and each year more than 200,000 newborns die. In rural Pakistan, more than 50% deliveries occur at home and majority by unskilled birth attendants(2). The country has a high proportion of preterm births and according to unpublished data it ranges between 15-20% of all live births. Prematurity is one of the 3 main causes of neonatal deaths (14.1%)(3). While many interventions exist to save the preterm newborns, KMC is considered as a simple, close to nature and cost-effective intervention. There are evidence to suggest that KMC, compared to incubator care, lowers the neonatal mortality by 51% for stable babies weighing <2,000 g if started in the first week. In this study; early, prolonged and continuous direct skin-to-skin contact is provided to preterm newborn by the mother or another family member to provide warmth and to encourage frequent and exclusive breastfeeding. The investigators intend to evaluate the impact of a KMC Package on the uptake of KMC in the community and its effect on neonatal mortality , exclusive breastfeeding rates , weight gain, neurodevelopment outcomes. This will be a cluster randomized controlled trial to be implemented in the rural union councils of District Dadu. The unit of randomization will be union councils.

NCT ID: NCT03431558 Recruiting - Clinical trials for Necrotizing Enterocolitis

Bovine Lactoferrin and Neonatal Survival in Low Birth Weight Babies.

Start date: May 1, 2018
Phase: Phase 3
Study type: Interventional

Pakistan has the third highest number of neonatal deaths worldwide. During the last two decades (1990-2013), neonatal mortality rate in the country has declined by only 1.0% per year. Severe infection is the second most leading cause of neonatal mortality, account for 28% of all deaths in Pakistan. Majority of neonatal deaths occur in infants who LBW (birth weight <2500g) and LBW comprises of both preterm / small for gestational age newborns. Breastfeeding helps protect infants from infections by serving as a source of nutrition uncontaminated by environmental pathogens. The protection is due to the multiple anti-infective, anti-inflammatory, and immuno regulatory factors transmitted through milk including secretory antibodies, glycan's, Lactoferrin, leukocytes, cytokines & other components produced by the mother's immune system. Reduction in neonatal infections and deaths is the aim of this study. The study is being conducted at the Aga Khan University in collaboration with University of Sydney.

NCT ID: NCT03381469 Recruiting - Metabolic Syndrome Clinical Trials

Periodontitis and Adverse Pregnancy Outcomes in Metabolic Syndrome Patients- Interventional Study

Start date: February 10, 2018
Phase: N/A
Study type: Interventional

Aim The Aim of the current study is to establish the association between periodontitis and adverse pregnancy outcomes in metabolic syndrome (Mets) patients and to evaluate the effect of intervention. Objectives 1. To evaluate the changes in periodontal status of pregnant women with metabolic syndrome after non surgical periodontal therapy (NSPT) 2. To evaluate the inflammatory marker levels in serum of pregnant women with metabolic syndrome after non surgical periodontal therapy 3. To evaluate the effect of NSPT on adverse pregnancy outcomes of women with metabolic syndrome

NCT ID: NCT03374033 Recruiting - Clinical trials for Infant, Very Low Birth Weight

High Protein and High Energy Intakes and Physical Activity on Growth of Extremely Low Birth Weight Infants

Start date: April 10, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effect of increasing amino acid and energy intake during parenteral and enteral nutrition with and without the stimulation of the infant's physical activity, on growth of extremely low birth weight infants .

NCT ID: NCT03223363 Recruiting - Birth Weight Clinical Trials

A New Birth Weight Prediction in Chinese Population

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

To determine the value of principal component analysis in the combined method of three-dimensional ultrasonography assessing fetal limb volume and circumference and conventional two-dimensional ultrasonography for prediction of birth weight in southern Chinese population.

NCT ID: NCT02817022 Recruiting - Clinical trials for Very Low Birth Weight Baby

Developmentally Supportive Care on Neurobehavioral Outcome of Preterm Very Low Birth Weight Neonates

DSC
Start date: January 2016
Phase: N/A
Study type: Interventional

Enrolled neonates will be provided routine supportive care as per existing neonatal intensive care unit (NICU)protocols. This will be carried out in the initial 6 months (0-180 days) of study commencement. This group will serve as control group (group A). During subsequent 6 months (181-360 days) of the study period, enrolled neonates fulfilling the inclusion criteria will be provided routine supportive care and the components of developmentally supportive care (DSC).

NCT ID: NCT02731092 Recruiting - Clinical trials for Very Low Birth Weight Infants

Safety and Tolerability of Lactoferrin in Very Low Birth Weight Infants

Start date: April 2016
Phase: Phase 1
Study type: Interventional

To evaluate the safety and tolerability of three different lactoferrin doses in preterm infants

NCT ID: NCT02105051 Recruiting - Risk Factors Clinical Trials

A Population-based Investigation of Related Factors of Birth Weight in China

Start date: n/a
Phase: N/A
Study type: Observational

The purpose of this study is to establish Chinese neonatal network to investigate current situation of neonatal birth weight and related factors. We investigated the risk factors such as sex, gestational age, region, nation, altitude, place of residence, maternal occupation, education level of mother, maternal age, maternal pregnancy diseases and multiple births.

NCT ID: NCT02016638 Recruiting - Clinical trials for Obstructive Sleep Apnea

Sleep Quality in Pregnancy and Its Impact on Pregnancy Outcomes

Start date: March 2013
Phase: N/A
Study type: Interventional

Hypothesis:Sleep Disorders are very common during pregnancy but the their exact role in causation of pregnancy related disorders is yet to be determined. OSA can complicate pregnancy given the risk factors of weight gain, upper displacement of the diaphragm, and hormonal-induced hyperaemia of the nasopharyngeal passages. SDB confers the risk of hypertensive disorders of pregnancy and is associated with adverse maternal and foetal outcomes. The study would involve pregnant females which would be prospectively followed in pregnancy and post partum to know the prevalence of sleep disorders in pregnancy. Diagnosis of sleep disorders would be confirmed by overnight polysomnography and ambulatory blood pressure monitoring. Pregnancy outcomes, both maternal and fetal would be recorded and its relation with sleep disorders in pregnancy would be analysed.