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Biological Specimens clinical trials

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

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NCT ID: NCT02473770 Withdrawn - Clinical trials for Biological Specimens

Rapid Acquisition of Pre- and Post-Incident Disaster Data

Start date: January 27, 2021
Phase:
Study type: Observational

Background: - Disasters like earthquakes, floods, and oil spills can give people health problems. Workers who respond to a disaster (like police and firefighters) are directly exposed to contaminants during the emergency response. So they could be at the greatest risk for these problems. Researchers want to gather data about these workers before and right after they go to a disaster. They hope this will help them understand the health effects of disasters. Objectives: - To answer questions about the health effects of disaster exposures. To create a participant registry and collect biological samples and health data. Eligibility: - People at least 21 years of age who are sent to a disaster area for an emergency response. Design: - Participants will have 1 study visit. - Participants will answer questions about: - Contact information - Health, lifestyle, emotions - Medical history - Disaster response activities - Things they are exposed to in the environment - Participants may have blood collected from a vein in the arm. - Participants may give biological samples. These may be urine, saliva, cheek cells, nail clippings, or hair. - Participants will have a short physical exam. They may have their hip and waist measured over their clothes. The amount of oxygen in their blood may be measured by a sensor on a finger or ear. - Participants may have a lung function test. They will take a deep breath and exhale strongly. - Participants will be asked to agree to be contacted later to update contact data and learn about future studies.