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Clinical Trial Summary

This is a single-arm, open, single-center Phase II clinical study to observe and evaluate the efficacy and safety of SBRT sequential surufatinib combined with immunotherapy in patients with locally unresectable or recurrent biliary tract cancer after the first surgery.


Clinical Trial Description

This is a single-arm, open, single-center Phase II clinical study to observe and evaluate the efficacy and safety of SBRT sequential surufatinib combined with immunotherapy in patients with locally unresectable or recurrent biliary tract cancer after the first surgery.The study was divided into three stages: screening period, treatment period and follow-up period. During treatment, imaging methods were used to evaluate tumor status every 6 weeks (±7 days) until disease progression (PD, RECIST 1.1) or death (during treatment) or toxicity became intolerable, and tumor treatment and survival status after disease progression were recorded. Safety outcome measures included AE, changes in laboratory test values, vital signs and electrocardiogram changes. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06199882
Study type Interventional
Source Zhejiang Cancer Hospital
Contact Luying Liu, M.D.
Phone 13957113195
Email luyingliu@163.com
Status Recruiting
Phase Phase 2
Start date February 1, 2024
Completion date June 30, 2026

See also
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