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Phase II Study of Refametinib, a MEK Inhibitor, as Second-line Treatment in Advanced Biliary Tract Adenocarcinoma

Biliary Tract Cancer Clinical Trial

Official title:
Phase II Study of Refametinib, a MEK Inhibitor, as Second-line Treatment in Advanced Biliary Tract Adenocarcinoma

Clinical Trial Summary

Phase II Study of Refametinib, a MEK inhibitor, as second-line treatment in advanced biliary tract adenocarcinoma

Clinical Trial Description

Refametinib will be administered orally at the starting dose of 50 mg twice daily on a continuous daily dosing schedule.

Self-administration of refametinib tablets will take place on an outpatient basis. Patients experiencing dose-limiting toxicity attributed to study medication should have at least 1-week treatment breaks inserted into the continuous daily dosing period as needed and/or may be interrupted or reduced depending on individual tolerability. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02346032
Study type Interventional
Source Samsung Medical Center
Contact
Status Completed
Phase Phase 2
Start date June 30, 2015
Completion date October 13, 2016
View Details
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