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Identification of Prognostic Gene Mutations in Biliary Tract Cancer Using Whole Genome Sequencing

Biliary Tract Cancer Clinical Trial

Official title:
Identification of Prognostic Gene Mutations in Biliary Tract Cancer Using Whole Genome Sequencing

Clinical Trial Summary

The purpose of this study is to investigate genetic mutations affecting prognosis using whole genome sequencing in patients with biliary tract cancer.

Clinical Trial Description

Recently, as genome technology such as next-generation sequencing has progressed, precision medicine using genetic analysis in lung cancer, colorectal cancer, and melanoma has been actively studied. The need for such precision medicine is also increasing in biliary tract cancer patients. Although whole genome sequencing is relatively costly, it is known to provide more accurate information than other methods such as exome analysis and RNA sequencing in identifying promoter mutations, regulatory regions, and structural variants. Pancreatic cancer and melanoma have been studied by whole genome sequencing, but there is no previous study using whole genome sequencing method in biliary tract cancer. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03718897
Study type Observational
Source Seoul National University Hospital
Contact Min su You, MD
Phone 82-2-2072-2228
Email bass105@hanmail.net
Status Recruiting
Phase
Start date September 14, 2018
Completion date September 2, 2022
View Details
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