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Benign Colorectal Neoplasm clinical trials

View clinical trials related to Benign Colorectal Neoplasm.

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NCT ID: NCT05643859 Recruiting - Clinical trials for Benign Colorectal Neoplasm

Impact of Dietary Fiber Supplementation on Colonic Mucosal Microbiome

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

This clinical trial tests whether daily fiber supplementation will change the mucosal microbiome of the colon. The microbiome are microorganisms that live in the human gut. They serve a vital role in maintaining health. Certain microbial strains are associated with the growth of colon polyps, which eventually could go on to form colon cancer. Giving dietary fiber supplements may help prevent precancerous polyps from ever developing.

NCT ID: NCT04247958 Completed - Clinical trials for Benign Colorectal Neoplasm

A Prospective Single-Center Evaluation of SureFormâ„¢ Staplers in Robotic-assisted Colorectal Procedures

Start date: January 30, 2020
Phase:
Study type: Observational

The primary objective of this study is to evaluate the performance of SureFormâ„¢ Staplers (60 and 45) for transection and/or creation of anastomosis during robotic-assisted colorectal procedures.

NCT ID: NCT01626963 Recruiting - Colorectal Cancer Clinical Trials

Single-port Versus Conventional Laparoscopic Colorectal Surgery

Start date: January 2014
Phase: Phase 1/Phase 2
Study type: Interventional

Conventional multi-port laparoscopic surgery (CL) is now a standard approach to colorectal resections, due to it's short-term benefits over conventional open surgery. In recent years, several studies have demonstrated that - in suitable patients - single-port access surgery (SPA) has similar clinical outcome compared to CL, with additional cosmetic benefits. It remains, however, unclear whether the trauma of surgery is also less for SPA compared to CL. In this study, the investigators aim to randomise patients who are deemed suitable for SPA surgery to either SPA approach, or CL; in addition to clinical outcomes including length of operating time, post-operative pain scores, complications, quality of life indicators and cosmetic appearance, the investigators aim to compare the physiological response to trauma through biochemical markers (including C-reactive protein, White Blood Cell count) and cytokine expression (i.e. Interleukins IL-6 and IL-8). Patients will be analysed according to intention-to-treat analysis, with 25 patients in the SPA and 25 patients in the CL group. The patients will be operated by surgeons proficient in both CL and SPA surgery, and followed-up for the duration of their hospitalisation as well as at their routine out-patient visits, using questionnaires.