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Skin Cancer and Hyperthermia and Radiotherapy — SAHARA  

Basal Cell Carcinoma Clinical Trial

Official title:
Skin Cancer and Hyperthermia and Radiotherapy - SAHARA a Two-arm, Open-label, Randomized Controlled Phase II Trial

Clinical Trial Summary

The SAHARA trial assesses wether combining ultrahypofractionated accelerated radiotherapy (RT) with hyperthermia is as effective as standard hypofractionated high-dose radiation in treating non-melanoma skin cancer (NMSC).

Clinical Trial Description

The SAHARA Trial is investigating if adding hyperthermia to radiotherapy (RT) can enhance treatment outcomes by making cancer cells more sensitive to radiation, thus requiring lower doses and potentially reducing side effects. The trial compares high-dose RT alone with de-escalated RT plus hyperthermia. The aim is to demonstrate that the combination is non-inferior to standard RT in treating non-melanoma skin cancer (NMSC). The trial is designed for elderly people of 65 years or older. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06384053
Study type Interventional
Source Kantonsspital Winterthur KSW
Contact Nidar Batifi, MSc
Phone 0522665361
Email study-coordination-radiotherapy@ksw.ch
Status Not yet recruiting
Phase N/A
Start date July 1, 2024
Completion date July 1, 2028
View Details
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