Basal Cell Carcinoma Clinical Trial
Official title:
Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma
Optical coherence tomography guided laser treatment of basal cell carcinoma
Status | Recruiting |
Enrollment | 40 |
Est. completion date | December 31, 2025 |
Est. primary completion date | December 31, 2025 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 99 Years |
Eligibility | Inclusion Criteria: - Ability to understand and carry out subject instructions or be represented by a legally authorized guardian or representative - Ages 18 and older - Seeks and is scheduled for treatment of a BCC previously confirmed with biopsy Exclusion Criteria: Any of the following will exclude participation in the study: - Inability to understand and/or carry out instructions - Patients with a BCC lesion that requires excision. This would include relatively large lesions (>2.5 cm diameter), lesions that penetrate deep into the skin beyond the depth of the OCT image capture, high risk lesions as defined by the American Academy of Dermatology as recurrent and sclerosing subtype BCC, or metastases. - Patients with periocular BCCs which might expose the patient to risk of damage to eyes from the laser. - BCCs on legs due to their tendency towards poor wound healing. - Pregnancy - Patients unable to follow-up for the full 12 months. |
Country | Name | City | State |
---|---|---|---|
United States | UCI Health Gottschalk Medical Plaza | Irvine | California |
Lead Sponsor | Collaborator |
---|---|
Christopher Zachary |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Complete clearance of BCC lesion | Those whose lesion is not in a cosmetically sensitive area will undergo a skin biopsy for histological confirmation of OCT results. | 1 year | |
Secondary | Cosmetic outcome | We assess cosmetic outcome and any adverse effects of the laser treatment as a result of the laser treatment, rated on a 0-4 Likert scaleworst cosmetic outcome and 4 resembling normal skin, upon follow-up of treatment. | 1 year |
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