Use Of Oral Itraconazole In Patients With Locally Limited Basocellular

Status Recruiting

Clinical Trial Summary

Patients with localized basocellular carcinoma of the skin, will receive oral Itraconazole, 200 mg twice daily, for 60 days, prior to curative intent surgery.

Clinical Trial Description

Patients with localized basocellular carcinoma of the skin, will receive oral Itraconazole, 200 mg once daily, for 60 days, before surgery with curative intent.

Tumor area regression will be measured through dermatologic evaluation and photographic documentation on baseline and at the end of the 60 day treatment period.

The activity of the Hedgehog pathway will be measured on tissue samples obtained at the time of diagnosis and at the time of curative intent surgery, through the measuring of the Ki67 index. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03972748
Study type	Interventional
Source	Hospital de Clinicas de Porto Alegre
Contact	Renato M Bakos, Ph. D.
Phone	+555133598000
Email	rbakos@hcpa.edu.br
Status	Recruiting
Phase	N/A
Start date	January 5, 2018
Completion date	June 1, 2021

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Use Of Oral Itraconazole In Patients With Locally Limited Basocellular Carcinoma Of Skin.

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms