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NCT01498250 Clinical Trial

Microarray Analysis of microRNA Expression in Basal Cell Carcinoma

Basal Cell Carcinoma Clinical Trial

Official title:
Microarray Analysis of microRNA Expression in Basal Cell Carcinoma

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01498250
Other study ID # microRNA6
Secondary ID
Status Completed
Phase N/A
First received December 20, 2011
Last updated October 15, 2012
Start date November 2011
Est. completion date December 2011

Study information
Verified date October 2012
Source Ruhr University of Bochum
Contact n/a
Is FDA regulated No
Health authority Germany: Ethics Commission
Study type Observational

Clinical Trial Summary

Perturbations in microRNA (miRNA) expression profiles has been reported for a variety of cancers. This study will be an exploratory analysis of miRNA expression in basal cell carcinoma by miRNA expression profiling using microarrays.

Description:

Perturbations in the expression profiles of microRNAs (miRNAs) have been reported for a variety of different cancers. Basal cell carcinoma (BCC) of the skin has not been systematically evaluated regarding differentially expressed miRNAs. Patients with BCC are included in the study to perform an exploratory analysis by miRNA expression profiling using microarrays. Expression levels of miRNA candidates will be validated by TaqMan real-time quantitative polymerase chain reaction (RT-PCR).

Recruitment information / eligibility
Status Completed
Enrollment 7
Est. completion date December 2011
Est. primary completion date December 2011
Accepts healthy volunteers No
Gender Both
Age group 1 Year and older
Eligibility Inclusion Criteria:

- Basal Cell Carcinoma

Exclusion Criteria:

- Other Skin Cancer than Basal Cell Carcinoma

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Germany Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum Bochum NRW

Sponsors (1)
Lead Sponsor Collaborator
Ruhr University of Bochum

Country where clinical trial is conducted

Germany, 

References & Publications (1)

Sand M, Skrygan M, Sand D, Georgas D, Hahn SA, Gambichler T, Altmeyer P, Bechara FG. Expression of microRNAs in basal cell carcinoma. Br J Dermatol. 2012 Oct;167(4):847-55. doi: 10.1111/j.1365-2133.2012.11022.x. Epub 2012 Aug 20. — View Citation

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