Basal Cell Carcinoma Clinical Trial
Official title:
Basal Cell Carcinoma Recurrence
NCT number | NCT00882791 |
Other study ID # | STU2538 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | May 2008 |
Est. completion date | May 2009 |
Verified date | November 2021 |
Source | Northwestern University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Basal cell carcinoma (BCC) is the most common skin cancer in the US and can cause significant adverse effects. Mohs micrographic surgery, the treatment of choice for higher risk BCC, allows for removal of lesions with preservation of healthy tissue. Although the BCC recurrence rate post Mohs surgery is estimated at 1-2%, recent data is lacking to validate this historical measurement. Our purpose is to determine the current recurrence rate of BCC after Mohs surgery.
Status | Completed |
Enrollment | 115 |
Est. completion date | May 2009 |
Est. primary completion date | May 2009 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Subjects with BCC lesions on the head, neck, genitalia, hands, or feet - Subjects who have undergone Mohs micrographic surgery for BCC on or before December 31, 2006 - Subjects with a medical record at the respective site - Subjects in a stable health condition, as determined by the principle investigator Exclusion Criteria: - Subjects with basal cell nevus syndrome - Subjects with lesions only in areas other than the head, neck, genitalia, - hands and feet - Subjects who have not followed up through the Department of Dermatology - Subjects with recurrent BCC lesions diagnosed on or prior to the recorded date of Mohs surgery |
Country | Name | City | State |
---|---|---|---|
United States | Northwestern University Feinberg School of Medicine, Department of Dermatology | Chicago | Illinois |
United States | DuPage Medical Group Dermatology | Naperville | Illinois |
Lead Sponsor | Collaborator |
---|---|
Northwestern University |
United States,
Dubin N, Kopf AW. Multivariate risk score for recurrence of cutaneous basal cell carcinomas. Arch Dermatol. 1983 May;119(5):373-7. — View Citation
Mehrany K, Weenig RH, Pittelkow MR, Roenigk RK, Otley CC. High recurrence rates of Basal cell carcinoma after mohs surgery in patients with chronic lymphocytic leukemia. Arch Dermatol. 2004 Aug;140(8):985-8. — View Citation
Robinson JK, Fisher SG. Recurrent basal cell carcinoma after incomplete resection. Arch Dermatol. 2000 Nov;136(11):1318-24. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Recurrence of BCC | either after 1 study visit (historical arm), or 3 years (prospective arm) | ||
Secondary | Risk Factors for recurrence of BCC | either after 1 study visit (historical arm), or 3 years (prospective arm) |
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