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Back Pain clinical trials

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NCT ID: NCT05260918 Completed - Pain, Chronic Clinical Trials

Examining the Effects of Float-REST for Recovery in Individuals With Chronic Lower Back Pain

Start date: February 24, 2022
Phase: N/A
Study type: Interventional

Researchers at the West Virginia University Rockefeller Neuroscience Institute are looking for volunteers to participate in a research study to evaluate what effects Float-REST (Restricted environmental Stimulation Technique) has on the stress response caused by chronic lower back pain.

NCT ID: NCT05254470 Completed - Back Pain Clinical Trials

Real-World Experience of Patients Treated for Musculoskeletal Injuries With SAM in Routine Care

Start date: September 1, 2020
Phase:
Study type: Observational

The purpose of this study is to evaluate continuous ultrasound treatment with diclofenac coupling patch during routine care of musculoskeletal injuries which failed conservative treatment to better understand clinical utilization of the treatment on types of injuries, how the treatment helps patients (pain, function and quality of life), and information on healthcare provider ordering the therapy and general workflow. Low-intensity continuous ultrasound (LICUS) is a bio regenerative technology used when normal rehabilitation is insufficient, applied with a wearable device (SAM, Zetroz Systems LLC) for daily use. The treatment provides long-duration ultrasound for approximately four hours. The objective of this study is to examine the real-world outcome data on symptoms improvement and return to function using SAM during routine care.

NCT ID: NCT05253599 Completed - Low Back Pain Clinical Trials

Radiographic and Inflammatory Biomarker Changes in Chronic Low Back Pain

Start date: November 1, 2019
Phase: N/A
Study type: Interventional

OBJECTIVE: To find and compare the effects of isokinetic training and virtual reality training on pain intensity, trunk muscle strength, radiographical (muscle cross-sectional area and muscle thickness), and biochemical effects in chronic low back pain (LBP) patients.

NCT ID: NCT05239247 Completed - Low Back Pain Clinical Trials

Effects of Eldoa Versus Meckenzie Exercise on Non-specific Low Back Pain Patients

Start date: October 30, 2021
Phase: N/A
Study type: Interventional

To determine the effects of Eldoa and Mckenzie exercises in posture. To determine the effects of Eldoa and Mckenzie exercises in ROM.

NCT ID: NCT05226156 Completed - Pain Clinical Trials

Digitally Delivered Exercise and Education Treatment for Low Back Pain: 3 Months Follow-up

Back3months
Start date: April 27, 2021
Phase:
Study type: Observational

Exercise and education is recommended as the first-line treatment by evidence-based, international guidelines for low back pain (LBP). Despite consensus regarding treatment, there is a gap between guidelines and what is offered to patients and less than half of the patients with nonspecific low back pain receive proper first-line care. The aim of this study was to examine the short-term effect in pain and function in people with nonspecific LBP, participating in the digitally delivered treatment program Joint Academy.

NCT ID: NCT05223946 Completed - Clinical trials for Low Back Pain, Recurrent

Treatment and Companion Diagnostics of Lower Back Pain Using SCENAR and Passive Medical Radiometry (MWR)

SCENAR/MWR
Start date: September 1, 2020
Phase: N/A
Study type: Interventional

Evaluation of the effectiveness of treatment of nonspecific pain in the lower back (LBP) is currently largely based on the patient's subjective feelings. The purpose of this study was to use passive medical radiometry (MWR) as a tool for assessing the effectiveness of various treatment methods in patients with acute and subacute nonspecific LBP. Patients with pain assessment on a visual analogue scale (VAS) from 6 to 10 points were divided into 2 groups: Group I included patients with pharmacological, syndrome-oriented treatment (n = 30, age 54.9 ± 2.3 years); Group II is a combination pharmacotherapy with self-controlled energy-neuro-adaptive regulation (SCENAR) (n = 25, age 52.8 ± 2.5 years). The investigators will compare that the addition of SCENAR therapy (Group II) will be able to potentiate the analgesic effect of the treatment using VAS. the investigators will confirm that the thermal asymmetry visualization allows to identify the area of pathological muscle spasm and/or inflammation in the projection of the vertebral-motor segment.

NCT ID: NCT05222724 Completed - Low Back Pain Clinical Trials

Efficacy of the Combination of Ibuprofen and Paracetamol in Acute Non-specific Low Back Pain

Start date: December 1, 2021
Phase: Phase 4
Study type: Interventional

The aim of the present study is to assess the efficacy and safety of paracetamol/ibuprofen Fixed Dose Combination (FDC) compared to ibuprofen in patients with uncomplicated non-specific acute low back pain after a 3-day treatment period.

NCT ID: NCT05221125 Completed - Clinical trials for Musculoskeletal Pain

Multimodal Management of Neck and Back Pain in the Emergency Department (Multi-ED)

Start date: June 6, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the feasibility and acceptability of psychologically-informed physical therapy (PIPT) in the ED in a pilot study of ED patients with neck or back pain. We will conduct a single-site, prospective trial comparing the combined program in one group with a usual care-only group. Primary outcomes will focus on feasibility based on recruitment and retention rates, and acceptability based on a 5-point patient satisfaction scale, while secondary outcomes will include pain severity, pain interference, anxiety, physical function, opioid use, repeat ED visits, and hospitalizations at 1 hour and at 24 hours, 1 month and 3 months after ED discharge. We will use pilot study results to develop a protocol for a larger pragmatic randomized clinical trial designed to rigorously evaluate PIPT in the ED combined with Spine Health follow up for ED patients with neck or back pain. We will perform a process evaluation of our proposed clinical trial study design, including characterizing and quantifying the degree of CBT and PT components used by treating PTs while in the ED and during Spine Health follow up, number of Spine Health visits attended in the first month, and integration into usual ED care. Qualitative interviews will be used to identify facilitators, barriers and potential solutions to intervention and research study procedures based on the patients' experience.

NCT ID: NCT05214690 Completed - Clinical trials for Rheumatoid Arthritis

A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of DW1809-T2

Start date: August 13, 2020
Phase: Phase 1
Study type: Interventional

Randomized, Open-label, Oral, Single-dose, two-Sequence, four-Period, crossover study

NCT ID: NCT05214677 Completed - Clinical trials for Rheumatoid Arthritis

A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of DW1809

Start date: August 15, 2020
Phase: Phase 1
Study type: Interventional

Randomized, Open-label, Oral, Single-dose, two-Sequence, four-Period, crossover study