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Clinical Trial Summary

The study is in two parts: a dose escalation then a safety dose expansion. The purpose of the dose escalation part is to evaluate the safety and tolerability of ascending doses of UCART19 (dose-escalation part) given as a single infusion in patients with relapsed / refractory (R/R) B-cell acute lymphoblastic leukaemia (B-ALL), to determine the maximum tolerated dose (MTD), the recommended dose and the lymphodepletion regimen. The purpose of the safety dose expansion is to assess the safety and tolerability of the RD for UCART19.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02746952
Study type Interventional
Source Servier
Contact
Status Completed
Phase Phase 1
Start date August 1, 2016
Completion date July 28, 2020

See also
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