Azoospermia Clinical Trial
Official title:
Follicle-stimulating Hormone Treatment for Infertile Male Patients With Non-obstructive Azoospermia: a Multicenter Randomized Clinical Trial
Aim of the study is to evaluate the effect of highly purified human follicle-stimulating hormone treatment on the chance of retrieving testicular sperm (sperm retrieval rate) from infertile male patients with non-obstructive azoospermia of unknown origin.
Preliminary reports showed that hormonal treatment may improve the chance of retrieving viable testicular sperm from men with NOA, but no RCT are available in the field. This randomized placebo-controlled clinical trial sought to evaluate whether the testicular sperm retrieval rate could result higher in NOA patients treated with follicle-stimulating hormone compared to placebo-treated NOA subjects. ;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04675164 -
Laser Assisted Sperm Selection of Viable Immotile Testicular Sperm in Azoospermic Infertile Men
|
N/A | |
Not yet recruiting |
NCT02617173 -
The Effect of Low Electrical Current on Testicular Spermatocyte Count
|
N/A | |
Completed |
NCT01375062 -
Obtaining Undifferentiated Cells From Testis Biopsy
|
N/A | |
Active, not recruiting |
NCT05134428 -
Safety Evaluation of the ADAM System
|
N/A | |
Active, not recruiting |
NCT05866484 -
Testicular Sperm Aspiration (TESA) vs. Microfluidic Sperm Separation (MSS)
|
||
Enrolling by invitation |
NCT03762967 -
Autologous Adipose-Derived Adult Stromal Vascular Cell Administration for Male Patients With Infertility
|
Phase 2 | |
Completed |
NCT00484081 -
Microdissection Testicular Sperm Extraction (MicroTESE) and IVF-ICSI Outcome in Non-Obstructive Azoospermia (NOA)
|
N/A | |
Recruiting |
NCT02418832 -
Testis Needle Aspiration of Sperm in Men With Azoospermia
|
N/A | |
Recruiting |
NCT02041910 -
Testicular Injection of Autologous Stem Cells for Treatment of Patients With Azoospermia
|
Phase 1/Phase 2 | |
Recruiting |
NCT02008799 -
Intra Testicular Artery Injection of Bone Marrow Stem Cell in Management of Azoospermia
|
N/A | |
Completed |
NCT01509482 -
Insulin Resistance in Idiopathic Oligospermia and Azoospermia
|
N/A | |
Completed |
NCT02339272 -
Study of Synapsis and Recombination in Male Meiosis and the Implications in Infertility
|
N/A | |
Completed |
NCT00548977 -
Genetic Studies Spermatogenic Failure
|
N/A | |
Recruiting |
NCT05479474 -
Platelet Rich Plasma Testis Treatment for Infertile Men
|
N/A | |
Recruiting |
NCT00282477 -
Trial to Evaluate Erectile Function, Fertility and Sperm Count in Male Cyclists Compared to Age Matched Controls
|
Phase 2 | |
Recruiting |
NCT05628987 -
The Association of Gut Microbiota and Spermatogenic Dysfunction
|
||
Recruiting |
NCT02544191 -
GnRHa Combined With hCG and hMG for Treatment of Patients With Non-obstructive Azoospermia
|
Phase 2 | |
Enrolling by invitation |
NCT02307994 -
Clinical Research on Effectiveness and Safety of Treatment of Severe Oligospermia or Azoospermia With uFSH
|
Phase 4 | |
Completed |
NCT02414295 -
Sperm Production in Kleinfelter Syndrome Patients After Mesenchymal Stem Cell Injection
|
N/A | |
Terminated |
NCT02773498 -
Comparison of Medical Results of Testicular Sperm Extraction by Conventional Surgery and Microsurgical Track
|
N/A |