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Clinical Trial Summary

Aim of the study is to evaluate the effect of highly purified human follicle-stimulating hormone treatment on the chance of retrieving testicular sperm (sperm retrieval rate) from infertile male patients with non-obstructive azoospermia of unknown origin.


Clinical Trial Description

Preliminary reports showed that hormonal treatment may improve the chance of retrieving viable testicular sperm from men with NOA, but no RCT are available in the field. This randomized placebo-controlled clinical trial sought to evaluate whether the testicular sperm retrieval rate could result higher in NOA patients treated with follicle-stimulating hormone compared to placebo-treated NOA subjects. ;


Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT02275169
Study type Interventional
Source Azienda Sanitaria Locale Bari
Contact Ettore Caroppo, MD
Phone +393479103660
Email ecaroppo@teseo.it
Status Not yet recruiting
Phase Phase 3
Start date February 2015
Completion date November 2016

See also
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Completed NCT02414295 - Sperm Production in Kleinfelter Syndrome Patients After Mesenchymal Stem Cell Injection N/A
Terminated NCT02773498 - Comparison of Medical Results of Testicular Sperm Extraction by Conventional Surgery and Microsurgical Track N/A