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Trauma as a Trigger for Autoimmunity — TATA  

Autoimmunity Clinical Trial

Official title:
Trauma as a Trigger for Autoimmunity - a Single Centre Observational Cohort Study

Clinical Trial Summary

To analyse the immunological reaction to Trauma (pertrochanteric femoral fracture with consequent osteosynthesis) in the first weeks up to one year postoperatively with focus on the development of autoimmunity.

Clinical Trial Description

This project represents a unique study of the influence of trauma on the immune system. It addresses the question whether an excess of apoptotic/necrotic cells can induce an at least transient autoimmune phenomena in humans. If the hypothesis of a transient induction of autoimmunity by trauma proves to be correct, this study will provide a novel insight into the pathogenesis of autoimmune diseases. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03767712
Study type Observational
Source University Hospital, Basel, Switzerland
Contact
Status Completed
Phase
Start date July 4, 2016
Completion date January 31, 2020
View Details
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