Clinical Trials Logo

Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT05884853
Other study ID # 202012163RIND
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date January 1, 2021
Est. completion date July 31, 2024

Study information

Verified date May 2023
Source National Taiwan University Hospital
Contact Yi-Ling Chien, MD, PhD
Phone +886223123456
Email chienyiling@gmail.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

"Social brain" refers to brain regions dedicated to processing social information and enabling us to recognize and evaluate others' mental states. The social brain hypothesis suggests that our brains evolve to navigate complex social systems. The social brain is hypothesized to consist of a distributed network including the posterior superior temporal sulcus (pSTS), the dorsal and ventral medial prefrontal cortices (dmPFC and vmPFC), ACC and posterior cingulate cortex (PCC), the amygdala, the orbital frontal cortex (OFC), and the fusiform gyrus (FG), TPJ, inferior occipital gyrus (IOG), and the insula. Each region serves distinct role while works together to support social processing, including perceiving, interpreting, and generating responses to the intentions, dispositions, and behaviors of others.


Recruitment information / eligibility

Status Recruiting
Enrollment 120
Est. completion date July 31, 2024
Est. primary completion date July 31, 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years to 50 Years
Eligibility Inclusion Criteria: - age between 18 and 50 - diagnosed with ASD from licensed mental health or medical professional based on DSM5 - have social problems - motivated to participate in the treatment - fluent in chinese - caregiver also fluent in chinese and motivated to participate - had a full-scale IQ > 70 on WAIS-IV - scored ? 26 on the caregiver-reported Autism Spectrum Quotient (AQ), indicating clinical impairment associated with ASD. Exclusion Criteria: - history of major mental illness, such as bipolar affective disorder, schizophrenia, psychosis, or neurological diseases - visual impairment and/or hearing impairment - any metal, electronic part that cannot be removed from the body, or being pregnant, which may not be able to use fMRI scan.

Study Design


Related Conditions & MeSH terms


Intervention

Behavioral:
PEERS
The Program for the Education and Enrichment of Relational Skills (PEERS®) studies is an evidence-based 16-week group-based social skill training program developed for adolescents and young adults with ASD.

Locations

Country Name City State
Taiwan National Taiwan University Hospital Taipei Zhongzheng Dist.

Sponsors (1)

Lead Sponsor Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type Measure Description Time frame Safety issue
Primary Autism Diagnostic Interview Revised, ADIR Interview of the caregivers that covers most developmental and behavioral aspects of ASD. Range from 0 to 8, higher the score, worse the symptom. 16 weeks
Primary The Autism Diagnostic Observation Schedule, ADOS Diagnosing and assess autism. Range from 0 to 8, higher the score, worse the symptom. 16 weeks
Primary Autism Spectrum Quotient 50 items, total score range from 0 to 50. Higher the score, worse the symptom 16 weeks
Primary Social Responsiveness Scale, Second Edition (SRS-2) 65 items, total score range from 65 to 260. Higher the score, worse the symptom 16 weeks
Primary Quality of Socialization Questionnaire (QSQ) 12 items, total score range from 0 to 12.Higher the score, better the frequency and quality of socialization 16 weeks
Primary The Empathy Quotient (EQ) 40 items, total score range from 0 to 80. Higher the score, worse the empathy 16 weeks
See also
  Status Clinical Trial Phase
Completed NCT05207956 - App for Strengthening Services In Specialized Therapeutic Support N/A
Completed NCT03286621 - Development of Eye-tracking Based Markers for Autism in Young Children
Completed NCT02608333 - Efficiency of Early Intervention for Autism Spectrum Disorder N/A
Recruiting NCT05935722 - Evaluation of a Home-based Parenting Support Program: Parenting Young Children N/A
Active, not recruiting NCT06259539 - A YouTube Curriculum for Children With Autism and Obesity N/A
Active, not recruiting NCT06303791 - Digital-based Psychosocial Intervention for Parents of Children With Neurodevelopmental Disorders N/A
Enrolling by invitation NCT05017779 - A Hybrid Effectiveness-implementation Trial of a High School-based Executive Function Treatment for Autistic Youth N/A
Completed NCT04772898 - Effectiveness of a 6-week Hippotherapy Program in Children With Autism Spectrum Disorder N/A
Recruiting NCT04987541 - The Therapeutic Effect of TBS Stimulation on Emotion Regulation in Autism Spectrum Disorder N/A
Completed NCT04308915 - Mobile-based Games for Cognitive Training in Children With Neurodevelopmental Disorders N/A
Completed NCT06038435 - The Effect of Cognitive Orientation Approach on Daily Occupational Performance With Autism Spectrum Disorder N/A
Terminated NCT04049981 - Investigation of Mechanisms of Action in Superpower Glass Phase 1/Phase 2
Completed NCT03693313 - The Effect of CrossFit Kids on Social Skills in Children With Autism Spectrum Disorder (CrossFit KAMP) N/A
Recruiting NCT04107064 - Achieving Steady Work Among Adults With Autism Through Specialized Employment Program N/A
Recruiting NCT03812068 - Parent-mediated Developmental Behavioral Intervention N/A
Completed NCT03206996 - Exposure Therapy for Auditory Sensitivity in Autism N/A
Completed NCT02299700 - Study to Evaluate the Janssen Autism Knowledge Engine in Children and Adults With Autism Spectrum Disorder N/A
Completed NCT03422016 - Electroretinogram in Autistic Spectrum Disorders
Active, not recruiting NCT03548779 - North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2 N/A
Recruiting NCT05114538 - Improving the Part C Early Intervention Service Delivery System for Children With ASD N/A