An Intervention Targeting Daily Adaptive Skills Through Executive Function Training for Adults With ASD

Autism Spectrum Disorder Clinical Trial

Official title:

An Intervention Program Targeting Daily Adaptive Skills Through Executive Function Training for Adults With Autism Spectrum Disorder: A Pilot Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04418492
• Other study ID #: B-1904/537-302
• Status: Completed
• Phase: N/A
• Start date: December 11, 2019
• Est. completion date: March 11, 2020

Study information

• Verified date: May 2020
• Source: Seoul National University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The current study is a single group pilot study of a novel intervention program which targets improvements in executive functions and adaptive skills in transition age young adults with high-functioning autism spectrum disorder. The main aim of the study is to test the effectiveness of the intervention using a pretest-posttest comparison. It is hypothesised that there will be an increase in executive functions and adaptive skills after the intervention.

Description:

The participants engaged in a 10-week group-based intervention program which aims to improve daily adaptive skills based on executive functions and help the transition into adulthood in young adults with ASD. Before and after the intervention, the participants and their parents completed questionnaires that measure executive functions and adaptive skills, and the participants additionally completed an assessment of social adaptive skills. The differences between pre- and post-intervention scores of the outcome measures were analyzed using Wilcoxon signed-rank tests to evaluate the effect of the program.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 7
• Est. completion date: March 11, 2020
• Est. primary completion date: March 11, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• A clinical diagnosis of ASD as measured by the Autism Diagnostic Observation Schedule and the Autism Diagnostic Interview-Revised

• Full-scale IQ of 70 or above as measured by the Weschler Adult Intelligence Scale

Exclusion Criteria:

• Full-scale IQ less than 70

• Uncooperative and lacking motivation to participate in the programme

• Reporting clinically significant behavioural problems, emotion regulation problems, psychotic symptoms, risk of self-harm or harm to others which can affect the participation to the programme, which is screened by the screening assessments and interviews.

Related Conditions & MeSH terms

• Autism
• Autism Spectrum Disorder
• Autistic Disorder
• Child Development Disorders, Pervasive
• High-functioning Autism

Intervention

Behavioral:
• Skills for Adaptive Functioning through Executive training (SAFE; tentative title)
An intervention program to improve adaptive skills and executive functions in young adults with high-functioning autism spectrum disorder was administered weekly for 10 weeks to the participants. The participants also completed pre-, mid- and post-intervention assessments.

Locations

Country	Name	City	State
Korea, Republic of	Seoul National University Bundang Hospital	Seongnam	Gyeonggi-do

Sponsors (1)

Lead Sponsor	Collaborator
Seoul National University Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The change in the Korean version of Barkley Deficits in Executive Functioning Scale (K-BDEFS)	The Korean version of Barkley Deficits in Executive Functioning Scale measures executive functions of adults in everyday life. The score range is 89-356. Higher score indicates worse executive functioning.	1 week before the intervention, between 5th and 6th session of the intervention and 1-3 week after the intervention.
Primary	The change in the Korean version of Vineland Adaptive Behavior Scale-II (K-Vineland-II)	The Korean version of Vineland Adaptive Behavior Scale-II measures adaptive behavior. The scores are converted into a standard score with a mean of 100 and a standard deviation of 15. Higher score indicates better adaptive functioning.	1 week before the intervention and 1-3 week after the intervention.
Primary	The change in the Community Integration Skills Assessment-2 (CISA-2)	The Community Integration Skills Assessment-2 measures adaptive skills necessary for people with developmental disorders to integrate into the community. The scores are converted into a standard score with a mean of 100 and a standard deviation of 15. Higher score indicates better community integration skills.	1 week before the intervention and 1-3 week after the intervention.
Primary	The change in the Cognitive Flexibility Inventory (CFI)	The Cognitive Flexibility Inventory assesses cognitive flexibility. The score range is 19-113. Higher score indicates better cognitive flexibility.	1 week before the intervention and 1-3 week after the intervention.