Neuropsychomotor Functions in Children With Autism Spectrum Disorder

Autism Spectrum Disorder Clinical Trial

Official title:

Neuropsychomotor Functions in Children With Autism Spectrum Disorder

Clinical Trial Details — Status: Unknown status

Administrative data

• NCT number: NCT01987037
• Other study ID #: 2013-A00644-41
• Status: Unknown status
• Phase: N/A
• First received: November 12, 2013
• Last updated: July 31, 2015
• Start date: October 2013
• Est. completion date: February 2016

Study information

• Verified date: July 2015
• Source: Centre Hospitalier Esquirol
• Contact: Aude Paquet
• Phone: 0033555431010
• Email: audepaquet[@]gmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of the study is to describe the feasibility of the passation of the assessment battery of psychomotor functions tests (NP-MOT) in children aged 4 to 11 years with a diagnosis of autism spectrum disorder: number and type of evaluable events, number and type of tests with a deficit compared to the standard results.

Description:

After informed consent obtention, the children will be submitted to the different tests of the battery to evaluate the psychomotor functions. The results will be compared with other data collected from the routine practise : socio-demographic data, medical and developmental antecedents,psychological tests (KABC II, Rey test, London Tower test, ...), psychomotor evaluation (MABC, evaluation of manual praxis, visual abilities, Frostig test), understanding data (N-EEL test), neuropediatric examination, clinical assessment (ADI-R, CARS).

The use of this battery allows this fine discriminative assessment of the psychomotor functions involved in the movement. Exploring each function will allow to take into account qualitative and quantitative aspects of the movement in every aspects, and this is not applied in the routine care until now. Calibration for each event can explore each function independently of each other, and will provide information to determine any specific developmental characteristics improve care.

Recruitment information / eligibility

• Status: Unknown status
• Enrollment: 40
• Est. completion date: February 2016
• Est. primary completion date: February 2016
• Accepts healthy volunteers: No
• Gender: All
• Age group: 4 Years to 11 Years

Eligibility

Inclusion Criteria:

• informed consent from the parents or the legal representative

• age 4 to 11

• autism spectrum disorder diagnosis according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition- text revised

Exclusion Criteria:

• bad understanding of the french language

• motor disability from lesion or accidental origin, proved genetic or neurologic disease

• deafness, blindness

• parents with administrative or judiciary protection, and without health insurance

Related Conditions & MeSH terms

• Autism Spectrum Disorder
• Autistic Disorder
• Child Development Disorders, Pervasive
• Disease

Intervention

Behavioral:
• neuropsychomotor assessment
Children with autism spectrum disorders pass a specific battery test (NP-MOT) for a neuropsychomotor assessment. This neuropsychomotor assessment is administered in a half-day maximum. This battery aims to investigate passive muscle tone (shoulders, limbs, and trunk), standing and synkinesia, static and dynamic balance, tonic laterality (extensibility and dangling of hands and feet to identify the tonic dominant side), laterality of use, fine-digit movements, digital tactile gnosis, and body spatial integration (knowing left from right: for oneself and that of others, and with regard to objects).

Locations

Country	Name	City	State
France	Centre de Ressources Autisme Limousin	Limoges
France	Centre Hospitalier esquirol	Limoges

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Esquirol

Country where clinical trial is conducted

France, 

References & Publications (1)

Lasserre E, Vaivre-Douret L, Abadie V. Psychomotor and cognitive impairments of children with CHARGE syndrome: common and variable features. Child Neuropsychol. 2013 Sep;19(5):449-65. doi: 10.1080/09297049.2012.690372. Epub 2012 Jun 14. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	results to the NP-MOT tests battery	the NP-MOT battery tests include several tests to evaluate 9 motor functions (muscle tone, gross motor, laterality, fine-digit movement, digital tactile gnosis, hand-eye skill, body spatial orientation, pace, auditory attention) with 48 subtests.; We describe: number and type of evaluable tests, number and type of tests with results with 1 Standard Deviation different from the standard results.; number and type of tests with results with 2 Standard Deviation different from the standard results.	one day