Impact of Probiotics on Children With ADHD

Attention Deficit Hyperactivity Disorder Clinical Trial

Official title: Effect of WecProB on Clinical Features and Gut Microbiota of Attention Deficit Hyperactivity Disorder in Children

Status Not yet recruiting

Clinical Trial Summary

To evaluate the efficacy and safety of probiotic product WecProB as food supplements for the treatment of clinical symptoms in children with ADHD, in comparison with placebo.

Clinical Trial Description

Randomized groups were given a combination of probiotics or placebo in addition to treatment with a consistent dose (1.2 mg/kg/d) of conventional ADHD medication (atomoxetine). The total length of the study is 12 weeks, and at weeks 0, 4, 8 and 12 weeks of the trial, the clinical symptoms of ADHD will be assessed using a scale. Blood and stool samples will be collected at weeks 0 and 12, and psychological tests will be performed. Nucleic acid sequencing technology was used to identify bacterial species in feces, and high-throughput 16S rRNA sequences were quickly obtained by sequencing, and fecal metabolites were analyzed. ;

Related Conditions & MeSH terms

• Attention Deficit Disorder with Hyperactivity
• Attention Deficit Hyperactivity Disorder
• Hyperkinesis

• NCT number: NCT06348121
• Study type: Interventional
• Source: Wecare Probiotics Co., Ltd.
• Status: Not yet recruiting
• Phase: N/A
• Start date: May 7, 2024
• Completion date: December 31, 2024