Attention Deficit Hyperactivity Disorder Clinical Trial
Official title:
An Open-Label Study of Naltrexone in Adults With Attention Deficit Hyperactivity Disorder.
The primary aim of this study is to assess whether naltrexone as a monotherapy is effective
in treating ADHD in adults. Medications that increase dopamine are often effective in
treating ADHD in adults. Since naltrexone is a kappa opioid receptor antagonist, it
increases dopamine in the brain.
We predict that naltrexone as a monotherapy will be effective for ADHD symptoms in adults
with ADHD. We also plan to assess the effects of naltrexone on dopamine as measured by
changes in serum prolactin. We predict that naltrexone will increase dopamine as indexed by
decreases in serum prolactin.
n/a
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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