Atrial Fibrillation Paroxysmal Clinical Trial
Official title:
Atrial Fibrillation Lifestyle Project
The objectives of the investigators are to demonstrate a reduction in frequency and symptoms of AF and improvements in cardiovascular risk factors following a lifestyle intervention in patients with paroxysmal AF. Participants will be randomized into control or intervention groups. The intervention will receive step trackers, diet counselling, an exercise program, and risk factor modification consultations. Controls will receive step trackers and care as usual. Testing will occur at baseline, six months, and one year.
Sixty percent of cases of non-valvular AF are associated with other modifiable risk factors,
including: obesity, diabetes, hypertension, or sleep apnea. Treating modifiable risk factors
has been shown to improve morbidity and mortality in patients with AF. Treatment of AF with
antiarrhythmic drugs or catheter ablation has not been shown to improve survival. Recently,
small cohort studies combining exercise, diet, and antiarrhythmic medications and/or ablation
have shown improvements in cardiovascular risk factors and reduction in AF symptoms and
frequency.
The aim of this study is to demonstrate a reduction in frequency and symptoms of AF and
improvements in cardiovascular risk factors following a lifestyle intervention in patients
with paroxysmal AF. This study uses a reproducible intensive supervised cardiac
rehabilitation that includes exercise, diet, and risk factor modification for patients with
paroxysmal, non-valvular AF. The investigators expect that a lifestyle intervention will show
significant improvement in fitness and weight loss and improvements in AF symptoms and
frequency, and cardiovascular risk factors when compared to a control group with paroxysmal
AF and similar baseline characteristics who do not receive a diet and exercise program.
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