Atherosclerosis of Artery Clinical Trial
Official title:
Prevalence of Atherosclerotic Carotid and/or Femoral Plaques in Patients Without Known Cardiovascular Disease and at Low-risk for Major Cardiovascular Events (AGLA/GLSA Score) Visiting a Private Primary Healthcare Practice in Switzerland
Cardiovascular disease is a common diagnosed and treated condition in private practices of
primary health care. There is growing evidence that atherosclerotic plaques as predictors for
stroke and heart attack are more prevalent than expected based on the clinical score in
people with low risk for stroke and heart attack .
Diagnosing atherosclerotic plaques can help to decide if a lipid lowering therapy should be
prescribed even if the clinical risk score is low or on the other hand if they can be
observed even in high lipid levels.
Both common and proximal internal carotid arteries and both common femoral arteries
(including bifurcations) were screened by ultrasound in patients who came for a check-up to a
primary care practice with no known cardiovascular disease and low risk for stroke and heart
attack according to the AGLA/GSLA risk score which is mostly used in Switzerland.
All patients agreed and gave written informed consent to be included in this study. Presence
of plaques was defined as a focal carotid intima-media thickness >0.5 cm on ultrasound.
Screening was performed by a medical doctor (DP) certified for the procedure using the
following ultrasound system: Toshiba Nemio XG, probe 7.5 MhZ.
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