Prevalence and Impact of Pertussis and RSV on Asthma Severity and Control — PRIPASCO  

Asthma Clinical Trial

Official title: Prevalence and Impact of Pertussis and RSV on Asthma Severity and Control

Status Recruiting

Clinical Trial Summary

The main objective is to estimate the annual symptomatic incidence of Bordetella pertussis and RSV infections in patients aged 18 years and over with asthma, which will be identified by PCR, for Bordetella pertussis and by PCR for RSV performed at a specific timepoint from onset of symptoms for each symptomatic Acute Respiratory Infection (ARI). A multicentre prospective cohort study will be undertaken in Spain. Thirty-five centres from different autonomous communities in Spain will participate in the study. Participants will be asked to report to the investigator if they experience an asthma exacerbation or symptoms of acute respiratory infection with 2 years follow up

Clinical Trial Description

The main objective is to estimate the annual symptomatic incidence of Bordetella pertussis and RSV infections in patients aged 18 years and over with asthma, which will be identified by PCR, for Bordetella pertussis and by PCR for RSV performed at a specific timepoint from onset of symptoms for each symptomatic Acute Respiratory Infection (ARI). A multicentre prospective cohort study will be undertaken in Spain. Thirty-five centres from different autonomous communities in Spain will participate in the study. Participants will be asked to report to the investigator if they experience an asthma exacerbation or symptoms of acute respiratory infection with 2 years follow up Depending on the symptoms presented and date of symptom onset, For pertussis, patients will undergo a nasopharyngeal swab specimen for PCR if onset of the symptoms was within the past 3 weeks For RSV, patients will undergo a nasopharyngeal swab specimen for PCR if onset of the symptoms was within the past 72 hours. ;

Related Conditions & MeSH terms

• Asthma
• Pertussis
• Respiratory Syncytial Virus Infections
• RSV Infection
• Whooping Cough

• NCT number: NCT06286007
• Study type: Observational [Patient Registry]
• Source: Hospital Clinico Universitario de Santiago
• Contact: Francisco-Javier GONZALEZ BARCALA, MD, PhD
• Phone: +34607819141
• Email: francisco.javier.gonzalez.barcala@sergas.es
• Status: Recruiting
• Start date: December 21, 2023
• Completion date: July 1, 2026