Asthma Clinical Trial - Asthma With Nasal Polyposis

Status Completed

Clinical Trial Summary

Asthma is often associated with various comorbidities that may influence its clinical expression. Among those, chronic rhinosinusitis with nasal polyposis (CRSwNP) is observed in 5% of cases. Asthmatic patients with CRSwNP appear to have more severe and poorly controlled asthma, as well as greater bronchial and systemic inflammation, especially those using inhaled corticosteroids as control medication. However, this remains to be validated. In the last decade, there has been interest labeled for phenotyping of asthma and CRSwNP. However, there is scarce data on the phenotype of asthma with CRSwNP.

This study aims to describe the phenotype of asthmatic patients with CRSwNP according to the clinical, physiological and inflammatory characteristics and whether there is a more severe phenotype related to the dose of inhaled corticosteroids and the percentage of induced sputum eosinophils.

Clinical Trial Description

This study will compare the characteristics of asthmatic patients with CRSwNP with those without CRSwNP. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03694847
Study type	Observational
Source	Laval University
Contact
Status	Completed
Phase
Start date	July 19, 2018
Completion date	September 15, 2018

View Details

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