Asthma Clinical Trial
Official title:
CHildhood ASthma and Environment Research Study - CHASER Study
"CHildhood ASthma and Environment Research study - CHASER study" is an observational longitudinal study in outpatient clinic of Pediatric Allergology & Pulmonology (PAP) of Respiratory Disease Research Center (RDRC) within the Institute of Biomedicine and Molecular Immunology (IBIM) of the National Research Council (CNR) of Palermo (RDRC-IBIM CNR), Italy. The first phase - transversal study will identify determinants of pediatric asthma control The second phase - longitudinal study, in patients with persistent asthma, will be focused on: - predictors for asthma exacerbations and loss of control - real life adherence to asthma therapy guidelines - phenotypic characterization through the collection of saliva samples - assessment of alterations and inflammatory changes in the nasal mucosa through nasal brushing - evaluation of the presence of 8-isoprostane, nicotine, cotinine and bisphenol-A through urine analysis. Chaser Project is expected to improve the knowledge of pediatric asthma in patients with different level of control, identifying predictors for asthma exacerbations and loss of control.
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