Asthma Clinical Trial
Official title:
HIV and Asthma in the Post-ART (Antiretroviral Therapy) Era
The purpose of this study is to determine the prevalence and severity of asthma in patients with HIV. To determine the immunological phenotype of HIV-infected patients with asthma.
Prospectively clinically phenotype and the prevalence of asthma in HIV infected patients in
the Duke ID Clinic
- HIV infected asthmatic subjects meeting clinical definitions for asthma compared to HIV
uninfected asthma subjects identified at the DAAAC and HIV infected non-asthmatic
subjects.
- Prospective immunological phenotyping - HIV-infected asthma subjects prospectively
identified and clinically phenotyped compared to HIV-uninfected asthma subjects
identified at the DAAAC and HIV infected non-asthma subjects.
Regarding the sampling method of probability sample: All samples for HIV infected asthmatic
patients, HIV uninfected asthmatic patients and HIV infected non-asthmatics patients will be
analyzed.
Retrospectively determine overall asthma prevalence and severity among HIV-infected patients.
Retrospective immunological phenotyping (circulating cytokines) of HIV-infected patients
utilizing available specimens in the Duke HIV Specimen Biorepository
- HIV-infected asthmatic subjects meeting asthma definition compared to overall asthma
prevalence in U.S. population
- HIV-infected asthma subjects meeting asthma definitions compared to matched HIV-infected
non-asthma subjects
;
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