Asthma Clinical Trial
Official title:
A Study on Inhaler Adherence to Improve Poor Asthma Control
The investigators hypothesize that aligning digital data on PEF and adherence with the
patient's own clinical course achieves better asthma control and identifies risks for future
loss of control, compared to current best practice. The study has an adherence optimisation
phase, week 1-12 followed by a medication management phase, week 12 to week 32.
The investigators will compare two asthma education interventions, standard Guideline
recommended practice and feedback from the individual's own INCA device, which assesses
inhaler adherence and relates adherence with changes in PEF and symptom scores over time.
The study has two co-primary endpoints, one will be a comparison of the adherence to therapy
and the other will be a comparison of the appropriateness of medication prescriptions between
the two study groups.
The investigators hypothesize that aligning adherence, inhaler technique and digitally
recorded PEF to inform patients and as the basis of prescribing decisions achieves better
inhaler adherence and technique and also allows physicians to make appropriate prescribing
decisions, compared to current best practice.
The investigators will compare two asthma education interventions, standard BTS/SIGN
Guideline recommended practice and feedback from the individual's own INCA device, which
assesses inhaler adherence and relates adherence with changes in PEF and symptom scores over
time.
This education phase is followed by a medication optimisation phase (weeks 12-32) in which
there are 3 cycles of medication optimisation guided by a digital script. The script either
adjusts the medications following the GINA recommendation or uses the GINA recommendation but
is supplemented with data on adherence and PEF that are recorded to digital, time-stamped,
recording devices.
The aim of the study is to improve and maintain adherence to preventer therapy, so that
medication and other costs as well as the quality of life, exacerbation rates are optimal.
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