Asthma Clinical Trial
Official title:
A Randomised, Double-blind, Placebo-controlled, Parallel-group, Multi-centre 24-week Study to Evaluate the Efficacy and Safety of Mepolizumab Adjunctive Therapy in Subjects With Severe Eosinophilic Asthma on Markers of Asthma Control
This is a multi-centre, placebo-controlled, double-blind, parallel-group study to evaluate
the efficacy and safety of mepolizumab adjunctive therapy in participants with severe
eosinophilic asthma on markers of asthma control. The overall intent of the current study is
to more fully explore the impact of mepolizumab on health-related quality of life (HR-QoL)
and other measures of asthma control, including lung function.
Participants who meet the predefined criteria will be randomised to receive either
mepolizumab or placebo in addition to standard of care asthma treatment. Approximately 780
participants with severe eosinophilic asthma will be screened to ensure the randomisation of
544 participants (272 participants per treatment group) into the study.
n/a
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