Effects of Regular Exercise on Adult Asthma

Asthma Clinical Trial

Official title:

Effects of Regular Exercise on Physical Fitness, Asthma Control and Quality of Life of Adult Asthmatics

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02012400
• Other study ID #: mjaakkola-001
• Status: Completed
• Phase: N/A
• First received: May 30, 2013
• Last updated: May 10, 2017
• Start date: August 2011
• Est. completion date: June 30, 2015

Study information

• Verified date: May 2017
• Source: University of Oulu
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to assess the effects of regular exercise on physical fitness, asthma control, and quality of life among adult asthmatics.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 131
• Est. completion date: June 30, 2015
• Est. primary completion date: June 30, 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 16 Years to 65 Years

Eligibility

Inclusion Criteria:

• diagnosis of asthma made by physician, or reimbursement for asthma medication from the National Social Insurance Institution of Finland (code 203), or patient fulfills the diagnostic criteria for asthma as outlined in the Finnish Guidelines for Asthma Management (Käypä hoito -suositus 2006 and 2012)

Exclusion Criteria:

• FEV1 < 60 % of predicted in spirometry

• PEF variability > 30 % at least 2 times during a 1-week monitoring period

• use of bronchodilating medication at least 4 times daily

• permanent, daily steroid tablet treatment

• patients who exercise regularly already at baseline at least 3 times a week at least 30 min at a time

• serious coronary heart disease

• severe hypotension

• severe heart failure

• severe musculoskeletal disorder

• dementia

• physician-diagnosed chronic obstructive lung disease

Related Conditions & MeSH terms

• Asthma

Intervention

Other:
• Exercise
The exercise group is given a 24-week individualized training program, including aerobic exercise, muscular training, relaxation exercises and stretching. Patients are asked to observe their asthma control daily and to mark in their diary asthma symptoms and activity limitations as well as duration, intensity and form of exercising on daily basis. They are also asked to perform PEF-measurements twice a day for one-week period every 4 weeks. The control group receives ordinary instructions.

Locations

Country	Name	City	State
Finland	Center for Environmental and Respiratory Health Research, University of Oulu	Oulu

Sponsors (8)

Lead Sponsor	Collaborator
University of Oulu	Foundation of the Finnish Anti-Tuberculosis Association, GlaxoSmithKline, Ida Montin Foundation, Jalmari and Rauha Ahokas Foundation, Oulu University Hospital, Research Foundation of the Pulmonary Diseases, Vaino and Laina Kivi Foundation

Country where clinical trial is conducted

Finland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Lung function	Lung function measured with spirometry	Baseline and 6 months
Other	Quality of Life	Quality of life assessed using St. Georges Respiratory Questionnaire	Baseline and 6 months
Other	Step test	Indirect maximal oxygen consumption test using with 6 min step-walk-test	Baseline and 6 months
Other	Muscle strength and flexibility	Muscle strength and flexibility tests	Baseline and 6 months
Primary	Asthma control	Asthma control based on symptom score and PEF-values	6-month period
Secondary	Physical fitness	Physical fitness measured with spiroergometry	Baseline and 6 months

External Links

•   Center for Environmental and Respiratory Health Research