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Anti-histamines and Methacholine Challenges.

Asthma Clinical Trial

Official title:
The Effect of Antihistamines on Methacholine Challenge Testing in Asthma Patients

Clinical Trial Summary

The asthmatic airway is identified and studied using inhaled agents such as histamine and methacholine. The use of antihistamines prior to the test will inhibit the test result if histamine is used to cause airway constriction. If using methacholine, this may also be true depending on whether old (e.g. benadryl) or new (e.g. desloratadine) antihistamines are used. This study will look at the effect of old and new antihistamines on inhaled methacholine challenge response in individuals with mild asthma.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01985789
Study type Interventional
Source University of Saskatchewan
Contact
Status Completed
Phase Phase 4
Start date November 2013
Completion date May 2014
View Details
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