Asthma Clinical Trial
Official title:
Bronchodilator Properties and Safety of a Repeated Dose of V0162 in Asthma.
Recent large clinical studies have demonstrated the interest of LAMA therapy in the
management of asthma, when compared to LABA.
V0162 is a compound with a very long lasting bronchodilator effect when compared to
reference treatment in non-clinical models and in COPD patients. Secondary properties of
V0162 (i.e.H1/H4 and PDE IV-inhibition) could enhance the efficacy of this antimuscarinic
compound and could bring option in the treatment obstructive lung disease. The objective of
the study is to assess the bronchodilator properties of V0162 during 8 days in adult
patients with asthma usually treated with ICS and LABA. The study is a randomised,
double-blind, placebo-controlled, 3-period crossover, preceded by an open-label
active-control period before randomisation.
n/a
Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double-Blind, Primary Purpose: Treatment
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