Asthma Clinical Trial
Official title:
Is a Low Salt Diet and Low Sugar Content Necessary When Corticosteroid Treatment is Prescribed?
Few recommendations concerning the diet and dosage to be administered to patients treated
with corticosteroids are established.
It therefore seems important to study prospectively the indication of a diet low in salt and
sugar in patients undergoing corticosteroid therapy, to record side effects observed and to
measure their frequency.
In the French clinical patterns governing the prescription of corticosteroids, it is
customary to prescribe a diet low in salt and low in sugar. This dietary prescription is
based on the interest of any diet to prevent the occurrence of side effects of steroids such
as hypertension, obesity, diabetes and congestive heart.
However, there is no specific dietary requirements in other European countries. This lack of
recommendations is based on the fact that there is no evidence that a strict diet reduces
the side effects of steroids on the one hand and secondly, that the quality of life of
patients undergoing a diet low in salt and low in sugars affects their quality of life. In
addition, no prospective study has helped to establish the frequency of side effects of
corticosteroids depending on dose and duration of treatment.
The investigators therefore propose to study whether a diet intervention with low salt or
low sugar during a prolonged corticosteroid treatment has any interest and effectively
reduces the frequency and severity of side effects.
The investigators propose that all parameters being equal, to randomize the diet of patients
started on steroids for a predictable period of 3 months minimum for a dose greater than 20
mg per day. One group will observe the low-salt diet, low in sugar and the other will follow
a normal diet. The assessment will be made after 1 year, even if steroid treatment is
continued beyond.
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Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label
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