Asthma Clinical Trial
Official title:
Analysing the Effects of Coupling Nebulization to Noninvasive Ventilation Through Pulmonary Scintigraphy on the Radioaerosol Deposition During Asthma Exacerbation
Despite the physiologic and clinical effects provided by coupling nebulization with noninvasive ventilation in asthma exacerbation, there are few and controversial studies reported in the literature.
Reduced work of breathing, increased oxygenation and increased in expiratory peak flow (EPF)
and forced expiratory volume in the first second (FEV1) are benefits of noninvasive
ventilation (NV) in the treatment of asthma. Despite these clinical improvements attributed
to NV during asthma exacerbations and the well-established effects of nebulization, there
are few studies in the literature coupling both therapeutic resources.
In addition to this, no studies on scintigraphic analysis of radioaerosol deposition coupled
with NV in asthmatics have published. A previous study was published by our group, but
involved healthy subjects.
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Allocation: Randomized, Intervention Model: Factorial Assignment, Masking: Open Label, Primary Purpose: Treatment
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