Screening Scottish Swimmers for Asthma and Rhinitis

Asthma Clinical Trial

— CLE004  

Official title:

A Pilot Study to Identify the Prevalence of Exercise- Induced Asthma and Rhinitis in Scottish Swimmers, Using Mannitol Challenge as a Screening Tool.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00831428
• Other study ID #: CLE004
• Status: Completed
• Start date: February 2009
• Est. completion date: June 2009

Study information

• Verified date: April 2019
• Source: University of Dundee
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The Scottish National and District swimming teams will be screened for asthma and rhinitis using both mannitol challenge and sport-based exercise challenge.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 97
• Est. completion date: June 2009
• Est. primary completion date: May 2009
• Accepts healthy volunteers: No
• Gender: All
• Age group: 11 Years to 23 Years

Eligibility

Inclusion Criteria:

• member of the Scottish national and district swimming team

• informed consent obtained

Exclusion Criteria:

• pregnant, lactating or planning to become pregnant

• concomitant use of medicines (prescribed, over-the-counter or herbal) that may interfere with the trial.

• any clinically significant medical condition, as deemed by the clinical investigators, which may endanger the health of the participant or jeopardise the protocol.

• inability to comply with the protocol.

Related Conditions & MeSH terms

• Asthma
• Rhinitis

Intervention

Other:
• no intervention
this is a screening study, not an interventional study

Locations

Country	Name	City	State
United Kingdom	The national swimming academy in Stirling	Stirling	Stirlingshire

Sponsors (1)

Lead Sponsor	Collaborator
Brian J Lipworth

Country where clinical trial is conducted

United Kingdom, 

References & Publications (1)

Clearie KL, Williamson PA, Vaidyanathan S, Short P, Goudie A, Burns P, Hopkinson P, Meldrum K, Howaniec L, Lipworth BJ. Disconnect between standardized field-based testing and mannitol challenge in Scottish elite swimmers. Clin Exp Allergy. 2010 May;40(5) — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Tidal Nitric Oxide		This test will be performed prior to entering the pool, and on exiting the pool
Secondary	Mannitol Challenge		This test will be performed once on a district and once on a national squad training day
Secondary	Sport-based Challenge		This test will be performed once on a district and once on a national squad training day
Secondary	Nasal Nitric Oxide		This test will be performed prior to entering the pool, and on exiting the pool
Secondary	Skin Prick Test		This test will be performed once on a district and once on a national squad training day
Secondary	Mini Nasal Lavage		This test will be performed prior to entering the pool, and on exiting the pool