Exercise Training in Asthma

Asthma Clinical Trial

Official title:

Comparison of Two Types of Exercise Training for Asthmatic Subjects : Interests and Limits

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT00820716
• Other study ID #: 3825
• Secondary ID: 2006-A00090-51
• Status: Terminated
• Phase: N/A
• Start date: September 21, 2009
• Est. completion date: October 15, 2010

Study information

• Verified date: August 2011
• Source: University Hospital, Strasbourg, France
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of the study is to compare two methods of exercise training: alternate load versus constant load realized at moderate or high intensities, in order to define the interests and the limits of each one of these two methods. The finality is to make possible to the expert to choose what exercise training induces the best results quickly and to make its choice according to the therapeutic objectives which it lays down.We also evaluate the effects of these exercises training on the vagal response and the bronchial tone of the asthmatics. From a clinical point of view, a close attention will be paid to the effects of these exercises training on the control of asthma and the quality of life of the subjects

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 2
• Est. completion date: October 15, 2010
• Est. primary completion date: October 15, 2010
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• 18 to 45 years old

• mild to moderate persistent asthma (GINA classification)

• stabilized asthma

• physical activity level between 5 and 11 (Baecke and coll, 1982)

• no contra-indication for physical training

Exclusion Criteria:

• cardiovascular pathology

• metabolic pathology

• traumatic pathology

• BMI=30

• tobacco

• diabetes

Related Conditions & MeSH terms

• Asthma

Intervention

Other:
• Exercise training
Comparison of two methods of exercise training: alternate load versus constant load realized at moderate or high intensities

Locations

Country	Name	City	State
France	Service de Physiologie et d'Explorations Fonctionnelles - Pôle de Pathologie Thoracique - Nouvel Hôpital Civil	Strasbourg
France	Service de Pneumologie - Pôle de Pathologie Thoracique - Nouvel Hôpital Civil	Strasbourg

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Strasbourg, France

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Maximal oxygen consumption (VO2max)		At T-1 = eight weeks before training - At T0 = beginning of training - At T1 = eight weeks after training
Primary	Maximal power output (Pmax)		At T-1 = eight weeks before training - At T0 = beginning of training - At T1 = eight weeks after training
Secondary	Exhaled NO (eNO)		At T-1 = eight weeks before training - At T0 = beginning of training - At T1 = eight weeks after training
Secondary	Heart rate variability		At T-1 = eight weeks before training - At T0 = beginning of training - At T1 = eight weeks after training
Secondary	Force Expiratory Volume in one second (FEV1)		At T-1 = eight weeks before training - At T0 = beginning of training - At T1 = eight weeks after training