Asthma Clinical Trial
To study the epidemiology of emergency asthma by focusing on three Multicenter Asthma Research Collaboration (MARC) databases collected over a two-year period in adult and pediatric emergency departments.
BACKGROUND:
The Multicenter Airway Research Collaboration (MARC) was created by 12 emergency physicians
in May 1996 to determine the best management of acute asthma in the emergency department.
The principal investigator of MARC, Dr. Carlos Camargo, formed the MARC Steering Committee
to help guide this collaboration. The MARC Coordinating Center is based at the Massachusetts
General Hospital (Boston, MA). Financial support for MARC has come from a variety of
sources, including government, foundations, and industry. The NHLBI study used MARC
databases.
DESIGN NARRATIVE:
Five representative aims were to: 1) characterize acute asthma management in urban emergency
departments (EDs) and then compare current practice with that recommended in the 1997
national guidelines; 2) examine gender differences in acute asthma; 3) identify reasons why
minority patients with asthma go to (and possibly prefer) the ED for their asthma care; 4)
characterize important clinical subgroups, such as acute asthma among pregnant women and
patients with sudden-onset severe acute asthma; and 5) examine risk factors for asthma
hospitalization and for relapse after ED discharge.
The study completion date listed in this record was obtained from the "End Date" entered in
the Protocol Registration and Results System (PRS) record.
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N/A
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