Asthma Clinical Trial
To identify risk factors which predispose individuals to develop asthma and other manifestations of allergic disease on exposure to laboratory animals in the workplace.
Status | Completed |
Enrollment | 0 |
Est. completion date | June 1990 |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Male |
Age group | N/A to 100 Years |
Eligibility | No eligibility criteria |
N/A
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
National Heart, Lung, and Blood Institute (NHLBI) |
Corn M, Koegel A, Hall T, Scott A, Newill C, Evans R: Characteristics of Airborne Particles Associated with Animal Allergy in Laboratory Workers. Ann Occup Hyg, 32:435-446 (Suppl 1), 1988
Eggleston PA, Ansari AA, Adkinson NF Jr, Wood RA. Environmental challenge studies in laboratory animal allergy. Effect of different airborne allergen concentrations. Am J Respir Crit Care Med. 1995 Mar;151(3 Pt 1):640-6. — View Citation
Eggleston PA, Ansari AA, Ziemann B, Adkinson NF Jr, Corn M. Occupational challenge studies with laboratory workers allergic to rats. J Allergy Clin Immunol. 1990 Jul;86(1):63-72. — View Citation
Eggleston PA, Kagey-Sobotka A, Proud D, Adkinson NF Jr, Lichtenstein LM. Disassociation of the release of histamine and arachidonic acid metabolites from osmotically activated basophils and human lung mast cells. Am Rev Respir Dis. 1990 Apr;141(4 Pt 1):960-4. — View Citation
Eggleston PA, Newill CA, Ansari AA, Pustelnik A, Lou SR, Evans R 3rd, Marsh DG, Longbottom JL, Corn M. Task-related variation in airborne concentrations of laboratory animal allergens: studies with Rat n I. J Allergy Clin Immunol. 1989 Sep;84(3):347-52. — View Citation
Evans R III, Fortney S, Menkes H, Newill C, Cohens BH: Biological Indicators of Susceptibility. In: Green GM, Baker F (Eds), Work, Health and Productivity. Oxford University Press, 1991.
Evans R III, Summers RJ, Newill CA: Allergic Reactions Caused by Exposure to Animals. In: Lichtenstein LM, Fauci AS (Eds), Current Therapy in Allergy, Immunology and Rheumatology - III. BC Decker Inc, Toronto, Philadelphia, p 5-7, 1988
Newill CA, Eggleston PA, Prenger VL, Fish JE, Diamond EL, Wei Q, Evans R 3rd. Prospective study of occupational asthma to laboratory animal allergens: stability of airway responsiveness to methacholine challenge for one year. J Allergy Clin Immunol. 1995 Mar;95(3):707-15. — View Citation
Newill CA, Prenger VL, Fish JE, Evans R 3rd, Diamond EL, Wei Q, Eggleston PA. Risk factors for increased airway responsiveness to methacholine challenge among laboratory animal workers. Am Rev Respir Dis. 1992 Dec;146(6):1494-500. — View Citation
Ziemann B, Corn M, Ansari AA, Eggleston P. The effectiveness of the Duo-Flo BioClean unit for controlling airborne antigen levels. Am Ind Hyg Assoc J. 1992 Feb;53(2):138-45. — View Citation
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