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Asthma, Exercise-Induced clinical trials

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NCT ID: NCT05703334 Completed - Clinical trials for Exercise Induced Asthma

Kt and Myofascial Release in Exc Asthma

Start date: January 20, 2023
Phase: N/A
Study type: Interventional

Purpose of this study was to compare between the effects of kinesio tap and myofascial release of respiratory muscles on exercise induced asthma

NCT ID: NCT04302610 Completed - Asthma Clinical Trials

Do Heat and Moisture Exchange Mask Reduce EIB and Cough Severity in Asthma

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

The overall aim of this study is to determine if face masks that can warm and humidify air can improve overall asthma control and markers of airway health during exercise in cold dry environments. We will investigate the potential protective benefits of the face masks against exercise induced asthma during 1) a "one-off" bout of exercise in a cold dry environment and 2) over the course of a four week period, exercising three times per week in a cold dry environment.

NCT ID: NCT04234464 Completed - Clinical trials for Exercise Induced Bronchospasm

A Study to Assess the Efficacy of Budesonide/Albuterol Metered-dose Inhaler (BDA MDI/PT027) on Exercise-induced Bronchoconstriction in Adults and Adolescents With Asthma

TYREE
Start date: January 15, 2020
Phase: Phase 3
Study type: Interventional

This is a multicenter, randomized, double-blind, single-dose, placebo-controlled, 2-period, crossover study to evaluate the efficacy and safety of budesonide/albuterol metered-dose inhaler (BDA MDI/PT027) as compared with a placebo metered-dose inhaler (placebo MDI) on exercise-induced bronchoconstriction (EIB) in adult and adolescent subjects with asthma. Subjects will receive each study treatment on separate visits and undergo a treadmill exercise challenge test for up to 10 minutes so that the effect of study treatment on exercise-induced bronchoconstriction can be evaluated.

NCT ID: NCT03840044 Completed - Clinical trials for Asthma, Exercise-Induced

The Effect of Physical Exercise in a Cold Air Environment on Normal Volunteers and Asthmatic Patients

ALASCAIR1
Start date: June 3, 2019
Phase: N/A
Study type: Interventional

The purpose of the study is to compare airway physiologic reactions to physical exercise in a cold air environment (-5°C, 60% relative humidity) between normal volunteers and subjects with mild/moderate asthma. For this purpose, the investigators intend to evaluate the effect of a cold air exercise test on the Forced Expiratory Volume in 1 second (FEV1), respiratory symptoms, functional airway integrity, local and systemic inflammation and on the airway microbiome. This study also features as an exploratory study for a subsequent interventional study in order to establish the feasibility of the cold air exercise protocol and to determine the extent of the effects in subjects with mild/moderate asthma.

NCT ID: NCT03550456 Completed - Clinical trials for Exercise Induced Asthma

Diagnostics and Quality of Life With EIA and EILO

Start date: November 1, 2018
Phase:
Study type: Observational

The purpose of this study is to investigate the quality of life of subjects suffering from dyspnoea while exercising and quantify the number of diagnoses of Exercise induced Asthma (EIA) and Exercise induced laryngeal obstruction (EILO) in our outpatient clinic using an exercise-challenge in a cold-chamber and an exercise-challenge with continuous laryngoscopy.

NCT ID: NCT02872675 Completed - Asthma Clinical Trials

The Effects of Prebiotics on Gut Bacterial Parameters, Immune Function & Exercise-Induced Airway Inflammation.

Start date: November 15, 2017
Phase: N/A
Study type: Interventional

The current study aims to explore the role of prebiotic supplementation in adults with and without Asthma/Exercise-Induced Bronchoconstriction (A/EIB). All participants will be asked to consume a prebiotic supplement, and a placebo, each for a total duration of four weeks, separated by a two-week wash out period. The investigators hypothesise that improvements in pulmonary function observed in adults with Asthma following prebiotic supplementation. We hypothesise that improvements in pulmonary function will be attributed, at least in part, to gut microbiota mediated improvements in human immune function.

NCT ID: NCT02410096 Completed - Clinical trials for Exercise-induced Asthma

Bronchial Inflammation and Hyperresponsiveness After Oil Supplementation

Start date: April 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the bronchial inflammation and hyperresponsiveness after oil supplementation. Before and after oil supplementation the investigators measure decrease in lung function after exercise-challenge in a cold chamber and increase of inflammatory markers in the blood.

NCT ID: NCT02026492 Completed - Clinical trials for Exercise-induced Asthma

Exercise Challenge in a Cold Chamber

Start date: June 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the exercise-challenge in a cold chamber at 2-4°C to the gold standard the metacholine challenge in subjects showing symptoms of exercise-induced bronchoconstriction. The sensitivity and repeatability of the exercise test will be measured.

NCT ID: NCT01942096 Completed - Clinical trials for Exercise Induced Asthma

Study of Airway Inflammation in Relation to Exercise in Elite Athletes

Start date: December 2011
Phase:
Study type: Observational

High school elite training programs are today more and more under development in several 'elite sport schools' in Belgium, in order to select and train future elite athletes already at young age. Little is known about the effects of sustained training on the potential development of asthma in adolescents during lung growth. It would be of great importance to be able to select the individuals at risk to develop exercise-induced asthma, already at the start of their enrollment in the 'elite sport school. This would allow physicians to follow their lung function parameters very closely and regularly; and, if necessary, start treatment early after the first signs of exercise-induced asthma.

NCT ID: NCT01691079 Completed - Clinical trials for Bronchospasm, Exercise-Induced

Effectiveness of Ipratropium Bromide in Preventing Exercise-induced Bronchoconstriction in Athletes

STAMINA
Start date: December 2012
Phase: Phase 4
Study type: Interventional

This will be a double-blind placebo-controlled study in which we plan to study 40 competitive endurance athletes. We will conduct an exercise test to evaluate maximal oxygen uptake and 2 exercise challenge tests to provoke EIA. Prior to the exercise challenge tests the athletes will randomly receive inhaled placebo or inhaled ipratropium bromide. We will compare the athletes' airway response to the exercise challenge with and without the active drug.