Clinical Trials Logo

Asthma, Exercise-Induced clinical trials

View clinical trials related to Asthma, Exercise-Induced.

Filter by:

NCT ID: NCT06336681 Recruiting - Clinical trials for Exercise Induced Asthma

Inspiratory Muscle Training on The Severity of Exercise-Induced Bronchoconstriction and Time-Trial Performance (IMT_EIB)

IMT_EIB
Start date: February 10, 2022
Phase: Phase 2
Study type: Interventional

Due to the lack of studies examining the impact of inspiratory muscle training (IMT) on the severity of exercise-induced bronchoconstriction (EIB) and exercise performance, the specific aim of this study is to assess the efficacy of flow-resistive IMT on EIB severity and symptoms, short-acting beta-2-agonist medication use, operating lung volumes, respiratory and limb locomotor muscle deoxygenation during constant-load cycling exercise, exertional dyspnea, and cycling time-trial performance.

NCT ID: NCT06245551 Recruiting - Clinical trials for Asthma, Exercise-Induced

A Study to Investigate the Effects of PT027 (Budesonide/Albuterol Sulfate) Metered-dose Inhaler Compared With Placebo on Exercise-Induced Bronchoconstriction in Adult Patients With Asthma

BREATH
Start date: December 22, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this Phase III, multicentre, randomized, double-blind, single-dose, 2-period, crossover study is to assess the efficacy and safety of PT027 (budesonide/albuterol sulfate) metered-dose inhaler compared with placebo on exercise-induced bronchoconstriction in adult patients with asthma. Subjects will receive each study treatment on separate visits and undergo a treadmill exercise challenge test so that the effect of study treatment on exercise-induced bronchoconstriction can be evaluated

NCT ID: NCT05703334 Completed - Clinical trials for Exercise Induced Asthma

Kt and Myofascial Release in Exc Asthma

Start date: January 20, 2023
Phase: N/A
Study type: Interventional

Purpose of this study was to compare between the effects of kinesio tap and myofascial release of respiratory muscles on exercise induced asthma

NCT ID: NCT05174689 Recruiting - Clinical trials for House Dust Mite Allergy

Epigenetic Regulation of Exercise Induced Asthma

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the micro ribonucleic acid (mRNA) profiles of patients with EIA without allergic sensitization and EIA with house dust mite sensitization compared to that of healthy controls.

NCT ID: NCT05162703 Enrolling by invitation - Clinical trials for Pediatric Respiratory Diseases

Evaluation of Exercise Induced Bronchoconstriction Using a Novel Automated Digital Clinical Decision System

Start date: September 27, 2021
Phase: N/A
Study type: Interventional

The primary objective of this study is to assess if the unstandardized field exercise challenge test (ECT) using AsthmaTuner can be performed independently by youths that have been investigated for asthma. This is an open feasibility study including youths who have been investigated for asthma. Participants will be equipped with a digital spirometer and mobile phone app to perform an exercise tests in their natural training environment. Feasibility will be evaluated using questionnaires.

NCT ID: NCT05105529 Recruiting - Asthma Clinical Trials

Adaptation to Ozone in Individuals With Asthma/Exercise-induced Bronchoconstriction

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Researchers found that impairments in the cardiopulmonary system caused by acute exposure to ozone were outweighed by repeated exposures to ozone. The goal of this study is to confirm there will be an adaptation similar to what was previously proved but in individuals with asthma and exercise-induced bronchoconstriction (EIB). The purpose is to examine adaptive responses in a randomized cross-over trial in which physically active individuals will perform submaximal exercise on five days in ozone and filtered air exposures separated by a washout period.

NCT ID: NCT04302610 Completed - Asthma Clinical Trials

Do Heat and Moisture Exchange Mask Reduce EIB and Cough Severity in Asthma

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

The overall aim of this study is to determine if face masks that can warm and humidify air can improve overall asthma control and markers of airway health during exercise in cold dry environments. We will investigate the potential protective benefits of the face masks against exercise induced asthma during 1) a "one-off" bout of exercise in a cold dry environment and 2) over the course of a four week period, exercising three times per week in a cold dry environment.

NCT ID: NCT04234464 Completed - Clinical trials for Exercise Induced Bronchospasm

A Study to Assess the Efficacy of Budesonide/Albuterol Metered-dose Inhaler (BDA MDI/PT027) on Exercise-induced Bronchoconstriction in Adults and Adolescents With Asthma

TYREE
Start date: January 15, 2020
Phase: Phase 3
Study type: Interventional

This is a multicenter, randomized, double-blind, single-dose, placebo-controlled, 2-period, crossover study to evaluate the efficacy and safety of budesonide/albuterol metered-dose inhaler (BDA MDI/PT027) as compared with a placebo metered-dose inhaler (placebo MDI) on exercise-induced bronchoconstriction (EIB) in adult and adolescent subjects with asthma. Subjects will receive each study treatment on separate visits and undergo a treadmill exercise challenge test for up to 10 minutes so that the effect of study treatment on exercise-induced bronchoconstriction can be evaluated.

NCT ID: NCT03840044 Completed - Clinical trials for Asthma, Exercise-Induced

The Effect of Physical Exercise in a Cold Air Environment on Normal Volunteers and Asthmatic Patients

ALASCAIR1
Start date: June 3, 2019
Phase: N/A
Study type: Interventional

The purpose of the study is to compare airway physiologic reactions to physical exercise in a cold air environment (-5°C, 60% relative humidity) between normal volunteers and subjects with mild/moderate asthma. For this purpose, the investigators intend to evaluate the effect of a cold air exercise test on the Forced Expiratory Volume in 1 second (FEV1), respiratory symptoms, functional airway integrity, local and systemic inflammation and on the airway microbiome. This study also features as an exploratory study for a subsequent interventional study in order to establish the feasibility of the cold air exercise protocol and to determine the extent of the effects in subjects with mild/moderate asthma.

NCT ID: NCT03610932 Withdrawn - Clinical trials for Exercise-induced Bronchospasm

Vitamin C & Exercise Induced Bronchoconstriction (EIB)

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

The purpose of this research is to assess the association between diet and pulmonary function during standardized EIB testing. Determine the effect of Vitamin C supplementation on airway inflammatory markers and bronchoconstriction after a standardized EIB test compared to usual diet and placebo control.