Articular Cartilage Defect Clinical Trial
Official title:
Introduction of Autologous Chondrocyte Implantation Procedure for the Treatment of Chondral Defect in the Knee
This study was aimed to evaluate effectiveness and safety of autologous chondrocyte suspension for treatment of knee articular cartilage defects.
- Prospective and interventional study - All procedures are carried out after obtaining informed written consent from patients. - Study procedures involve a biopsy, cell production, cell implantation and follow-up including a strict post-surgery rehabilitation protocol (12 month timepoint) - All subjects will be assessed at intervals post-implantation (6 weeks, 3 months, 6 months and 12 months). - Measures to assess effectiveness and safety will be conducted at follow-ups: Magnetic Resonance Imaging (MOCART score), collection of adverse events, orthopaedic scores (KOOS, IKDC, SF12v2) ;
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