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Clinical Trial Summary

The goal of this clinical trial is to evaluate the effectiveness and safety of autologous costal osteochondral transplantation in the treatment of Hepple Stage V talar osteochondral lesions, compared with autologous osteoperiosteal transplantation. The main question it aims to answer is: • Whether autologous costal osteochondral transplantation can achieve better clinical outcomes and cartilage repair quality with lower donor site morbidity than autologous osteoperiosteal transplantation in the treatment of Hepple Stage V talar osteochondral lesions. Participants will be randomly assigned to the intervention group (undergoing autologous costal osteochondral transplantation) or the control group (undergoing autologous osteoperiosteal transplantation). Both groups of participants will receive the same postoperative rehabilitation process and follow-up evaluation.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05942430
Study type Interventional
Source The Third Affiliated Hospital of Southern Medical University
Contact Hao Guo, MD
Phone +8617612003968
Email 416363977@qq.com
Status Recruiting
Phase N/A
Start date September 1, 2023
Completion date February 2028

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